| 何君君.鲍曼不动杆菌感染的临床分布及其耐药情况[J].浙江中西医结合杂志,2014,24(1): |
| 鲍曼不动杆菌感染的临床分布及其耐药情况 |
| Clinical distribution and analysis of drug resistance of Acinetobacter baumannii infection |
| 投稿时间：2013-04-20 修订日期：2013-04-20 |
| DOI： |
| 中文关键词: 鲍曼不动杆菌 临床分布 耐药性 |
| 英文关键词:Acinetobacter baumannii Distribution Drug resistance |
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| 中文摘要: |
| 目的 了解鲍曼不动杆菌感染的临床分布及其耐药情况，为临床抗菌药物的选择提供依据。方法 回顾性分析2011年1月-2013年1月本院各类临床标本分离的鲍曼不动杆菌的临床分布特点及药敏结果。结果 2011年1月-2013年1月共检出鲍曼不动杆菌 198株，分离率为5.2 %。标本来源以痰液为主，占40.4.%。科室分布以重症医学科最多，占 41.4 %，其次是呼吸内科，占17.2%。鲍曼不动杆菌对复方氨苄西林的耐药率最为严重，已达70%以上；对替卡西林、替卡西林/棒酸、哌拉西林、哌拉西林/他巴唑、头孢他定、头孢吡肟、、环丙沙星和复方磺胺甲恶唑的耐药率也已达60%以上；头孢哌酮/舒巴坦的敏感性良好，耐药率均在10%以下。结论 鲍曼不动杆菌的分离率和耐药性逐年上升，应连续监测其耐药性变化，合理选用抗菌药物，同时加强医院感染控制，防止耐药菌株的播散。 |
| 英文摘要: |
| OBJECTIVE To investigate the Clinical of distribution and antibiotic resistance of acinetobacter baumannii, providing reference for clinical treatment. METHODS Clinical distribution and drug resistance of acinetobacter baumannii isolated from various clinical specimens of the infections from Huzhou Chinese medicine hospital during In 2011 January -2013 year in January were retrospectively analyzed. RESULTS A total of 198 strains of acinetobacter baumannii were isolated during the In 2011 January -2013 year in January,the isolation rate was 5.2%. Specimens of sputum-oriented sources（40.4%）. Section distribution was mainly on ICU ward(41.4%), followed by department of Respiratory Medicine (17.2%) .The result of drug sensitive test showed that the resistance rates of Acinetobacter baumanniithe resistance rates to compound ampicillin were more than 70%, ticarcillin, ticarcillin/clavulanic acid,piperacillin and piperacillin/tazobactam,ceftazidime,cefepime,ciprofloxacin and compound sulfamethoxazole were more than 60%. the resistance rate of cefoperazone/sulbactam was below the 10%. CONCLUSIONS The isolation rate and drug resistance of Acinetobacter baumannii upward trend, it is mandatory for hospital to arrange a continuous monitoring its suscepitility ,choose the antibiotics reasonably and control the hospital infection strengthenly,so as to prevent the spread of multidrug-resistant acinetobacter baumannii strains. |
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