| 石钢,张新根,曹铨,孙贤杰,方铭,翁科迪.老年髋部骨折围手术期D-二聚体与深静脉血栓相关性的临床研究[J].浙江中西医结合杂志,2014,24(10): |
| 老年髋部骨折围手术期D-二聚体与深静脉血栓相关性的临床研究 |
|
| 投稿时间：2013-12-16 修订日期：2014-08-20 |
| DOI： |
| 中文关键词: 老年髋部骨折 D-二聚体 深静脉血栓形成 围手术期 |
| 英文关键词: |
| 基金项目:嘉兴市科技局项目，编号：2012AY1077-1 |
|
| 摘要点击次数: 1156 |
| 全文下载次数: 0 |
| 中文摘要: |
| 【】 目的 探讨老年髋部骨折围手术期血浆D一二聚体动态检测对深静脉血栓(DVT)形成早期诊断中的临床意义。方法 2009年11月至2012年10月,采用乳胶凝集免疫比浊法,于入院当天、术前1天和术后1、3、5、7、9、14天采集静脉血样动态测定本院102例老年髋部骨折患者血浆D-二聚体浓度,分析其动态变化特点。按照彩超检查结果将患者分为DVT组与非DVT组,比较两组各时间点的D-二聚体水平。结果 与术前相比,102例患者术后血浆D-二聚体浓度均升高,术后1天即达2000 ug／L以上,其中有l0例D-二聚体浓度呈持续性或进行性升高,术后5d达高峰(4427±324) ug／L,并呈持续升高状态,术后14 d仍有(2622±96)ug／L,而其他92例患者D-二聚体值能较快地下降,其峰值仅持续3d,术后5d即降至2000ug／L以下。双下肢深静脉彩超检查后确认10例持续升高患者发生DVT(DVT组),92例D-二聚体水平迅速下降患者未发生DVT(非DVT组),DVT的发生率为9.8％。与非DVT组比较,DVT组患者术前D-二聚体水平接近,术后1d和术后3、5、7、9、14d 的D-二聚体水平均升高(均P<0．05)。结论 高龄老年髋部骨折围手术期血浆D-二聚体浓度的动态监测对术后并发DVT早期诊断具有重要价值。 |
| 英文摘要: |
| The clinical study of correlation between perioperative D-dimer of elderly hip fracture and deep vein thrombosis.
SHI Gang,ZHANG Xingen,CAO Quan,WENG Kedi,SUN Xianjie,FANFG Ming. Zhejiang Rongjun Hospital,Jiaxing(314000),China.
ABSTRACT Objective Explore elderly hip fracture perioperative plasma D dimer of just a dynamic detection of deep vein thrombosis (DVT) to form the clinical significance of early diagnosis. Methods In November 2009 to October 2012, the latex agglutination immune turbidimetric method, on the day of admission, preoperative and postoperative 1, 3, 5, 7, 9, 14 days collecting venous blood dynamic measurement in our hospital 102 cases of senile hip fracture in aged patients plasma D-dimer concentration, to analyze its dynamic characteristics. According to the Color ultrasound examination results divided the patients into DVT with the no DVT group, compared two groups of each time point D-dimer level. Results 92 cases of postoperative not DVT,10 cases of postoperative occurred DVT,the incidence of DVT was 9.80%, DVT group postoperative D-dimer levels have persistent rise,postoperative 5 D peak (4427±324) of ug/L, and continue to rise, after 14 D still have (2622±96 )ug/L, and the other 92 patients D-dimer values can rapidly declined, its peak last only 3 D, 5 D which dropped to below 2000 ug/L.Compared with the group of no DVT, The patients preoperative D-dimer levels did not differ between the two groups（P＞0.05）, but DVT group postoperative D-dimer levels were observably elevated (P<0.01).. Conclusion dynamic monitoring concentration of plasma D-dimer of perioperative of elderly hip fracture is of important value to the early diagnosis by DVT .
KEY WORDS elderly hip fracture; D-dimer; Deep venous thrombosis; perioperative |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
