| 陆娟英,江荣林,张永建.香砂六君子汤预防危重病脾胃虚弱型患者胃肠功能障碍的临床观察[J].浙江中西医结合杂志,2015,25(1): |
| 香砂六君子汤预防危重病脾胃虚弱型患者胃肠功能障碍的临床观察 |
| Observe the clinical efficacy of Xiang Sha Liu Jun Zi Decoction in Preventing critically ill patients with weak spleen and stomach from gastrointestinal dysfunction. |
| 投稿时间：2014-05-07 修订日期：2014-08-01 |
| DOI： |
| 中文关键词: 香砂六君子汤 脾胃虚弱型 胃肠功能障碍 |
| 英文关键词:Xiang Sha Liu Jun Zi Decoction Weak spleen and stomach Gastrointestinal dysfunction |
| 基金项目:浙江省中医药防治重大疾病攻关计划2012ZGG001通讯作者江荣林(1964~),男,汉族,浙江温岭人,主任医师,硕导,医学硕士,研究方向危重病的中西医结合治疗。电话：13958095268,Email: jiangronglin@126.com 香砂六君子汤预防危重病脾胃虚弱型患者胃肠功能障碍的 |
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| 中文摘要: |
| 【】 目的 研究早期使用香砂六君子汤对预防危重症脾胃虚弱型患者胃肠功能障碍的效果。方法 将120例诊断为危重症脾胃虚弱型患者,随机分成2组：对照组(58例)按常规治疗,治疗组(62例)在对常规治疗基础上早期运用香砂六君子汤,观察比较2周内两组患者胃肠功能障碍(GIDF)的发生情况以及两组治疗前后血清胃动素(MLT)、C反应蛋白(CRP)及降钙素原(PCT)的变化。结果 两组患者的血清MLT于治疗2 周后较治疗前显著升高(P<0.05)；且治疗组较对照组显著升高(P<0.05)。两组患者的血清CRP、PCT于治疗2 周后较治疗前均有显著降低(均P<0.05)；且治疗组较对照组显著降低(P<0.05)。治疗组较对照组2周内胃肠功能障碍的发生率显著减少(分别为19.35%和36.21%,P<0.05)。结论 早期使用香砂六君子汤可提高危重症脾胃虚弱型患者的血清胃动素水平,降低血清C反应蛋白和降钙素原的水平,显著减少胃肠功能障碍的发生。 |
| 英文摘要: |
| 【】 Objective To observe the clinical efficacy of Xiang Sha Liu Jun Zi Decoction in Preventing critically ill patients with weak spleen and stomach from gastrointestinal dysfunction. Method 120 critically ill patients with weak Spleen and stomach were randomly divided into two groups : The control group( 58 cases ) takes routine therapy, pointing to symptoms; The treatment group (62 cases) takes Xiang sha Liu jun zi Decoction early on the basis of control group. The incidence was observed comparing the occurrence of gastrointestinal dysfunction (GIDF) within two weeks, and the serum motilin (MLT) 、C- reactive protein(CRP) and Procalcitonin (PCT) level changed before and after treatment .Result The two groups both achieved significant improvement in serum motilin (MLT) level after treatment (P<0.05). There was a significant difference in comparing motilin (MLT) level between the two groups after treatment (P<0.05). The two groups both achieved significant decline in C- reactive protein and Procalcitonin level after treatment (P<0.05). There was a significant difference in comparing C- reactive protein and Procalcitonin level between the two groups after treatment (P<0.05). Compared with the control group,GIDF incidence of the treatment group were significantly reducing within two weeks(19.35% and 36.21% respectively,P<0.05). Conclusion Early use of Xiang Sha Liu Jun Zi Decoction can increase critically ill patients with weak Spleen and stomach on serum motilin level ,and decrease their CRP, PCT level ,and reduce the incidence of GIDF. |
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