| 余捷.磁共振扩散加权成像对小肝癌鉴别诊断的应用价值[J].浙江中西医结合杂志,2015,25(2): |
| 磁共振扩散加权成像对小肝癌鉴别诊断的应用价值 |
| The application apparent diffusion coefficient values in the diagnosis of suspicious small hepatocellular carcinoma |
| 投稿时间：2014-06-04 修订日期：2014-06-04 |
| DOI： |
| 中文关键词: 扩散加权成像 ADC值 小肝癌 诊断 |
| 英文关键词: |
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| 中文摘要: |
| 【】目的 研究磁共振扩散加权成像(MR-DWI)及表观扩散系数(ADC值)在可疑小肝癌(SHCC)鉴别诊断中的应用价值。方法 对89例可疑SHCC病例同时行常规MRI检查和DWI检查,通过分析ADC值,并将小肝癌与非小肝癌的ADC值进行ROC分析,以确定诊断可疑小肝癌的合适ADC值。结果 89例可疑小肝癌患者经手术病理或临床确诊为小肝癌的患者36例,非小肝癌患者53例,其中肝囊肿14例,肝血管瘤31例,肝转移瘤8例。36例SHCC患者的ADC均值为(1.027±0.285)×10-3mm2/s,显著低于肝实质的ADC值[(1.214±0.324)×10-3mm2/s, t=7.536, P<0.01],显著低于非SHCC患者的的ADC值为(2.119±0.615)×10-3 mm2/s(t=16.01, P<0.001)。当ADC临界值≤1.133×10-3mm2/s时,敏感性为84.27％,特异性为94.32％,准确性为87.48％。结论 小肝癌的ADC值小于肝实质的ADC值,也小于非小肝癌的ADC值,ADC值在可疑SHCC的鉴别诊断中具有临床应用价值。 |
| 英文摘要: |
| 【】Objective To investigate the application value of diffusion-weighted imaging and apparent diffusion coefficient values in the diagnosis of suspicious small hepatocellular carcinoma. Methods 89 patients with suspicious small hepatocellular carcinoma underwent both routine MRI and DWI scanning, apparent diffusion coefficient (ADC) value of each patients were statistical analyzed, and the subjects ability to line working curve (ROC) analysis was assigned to evaluate the ADC values of SHCC and non-SHCC to determine the cutoff point of ADC values for the diagnosis of SHCC. Results 89 patients with suspicious small hepatocellular carcinoma were diagnosed with 36 SHCC, 14 dysplastic nodules, 31 angioneoplasm and 8 hepatic metastatic tumor. The mean values of ADC of SHCC patients were (1.027±0.285)×10-3mm2/s, which was significantly lower than that of normal liver tissue [(1.214±0.324)×10-3mm2/s, t=7.536, P<0.01], and significantly lower than that of non-SHCC patients (2.119±0.615)×10-3 mm2/s(t=16.01, P<0.001). When the cutoff points of ADC value was set at ≤1.133×10-3mm2/s, the sensitivity, specificity and accuracy was 84.27%, 94.32% and 87.48%, respectively. Conclusion The mean values of ADC of SHCC patients are lower than that of non-SHCC patients. ADC has clinical application value in the diagnosis of suspicious small hepatocellular carcinoma. |
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