| 赵小兴,徐萍,丁蓉.通络止痛方治疗带状疱疹后遗神经痛的临床观察[J].浙江中西医结合杂志,2015,25(11): |
| 通络止痛方治疗带状疱疹后遗神经痛的临床观察 |
| Clinical Observation of Tongluo Zhitong Decoction in Treating Postherpetic Neuralgia |
| 投稿时间：2015-03-25 修订日期：2015-03-25 |
| DOI： |
| 中文关键词: 通络止痛方 加巴喷丁 带状疱疹后遗神经痛 |
| 英文关键词:Tongluo Zhitong Decoction Ganapentin Capsule Postherpetic Neuralgia |
| 基金项目: |
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| 中文摘要: |
| 目的 观察中药通络止痛方治疗带状疱疹后遗神经痛的临床疗效和安全性。方法 150名病人随机分为治疗组和对照组各75例,两组在同时口服甲钴胺的基础上,治疗组用自拟的通络止痛方,一日一剂；对照组用加巴喷丁胶囊,一日三次,每次300mg。两组均治疗二月,每半月观察一次,详细记录视觉模拟评分法(VAS)的分值与不良反应。结果 疗程结束时治疗组有效率为60%,对照组为58.7%,差异无统计学意义(P＞0.05)；VAS的分值组内前后下降差异有统计学意义(P＜0.05),组间下降无统计学意义(P＞0.05)；治疗组不良反应发生率为21.3%,而对照组为57.3%,差异有统计学意义(P＜0.05)。结论 通络止痛方治疗带状疱疹后遗神经痛比加巴喷丁更具有优势。 |
| 英文摘要: |
| Objective To observe the efficacy and safety of Tongluo Zhitong Decoction in the treatment of the Postherpetic Neuralgia． Methods One hundred and fifty outpatients were randomly divided into treatment group and contrant group,each contains 75 cases．All patients were treated with Methycobal tablets (500ug)(3 times/day)．Additionlly,treatment groups were treated with Tongluo Zhitong Decoction() and contrant groups were treated with Ganapentin Capsule(3 tablets/times,3times/day)．Both groups were treated for 2 months．The visual analogue scale(VAS) and adverse reaction were evaluated every half month．Results The efficient rate for the treatment group and the contrant group was respectively 60.0% and 58.6%,with no difference between them (P＞0.05)．The patients,VAS scores of the two groups were decreaced after treatment,with no difference between them (P＞0.05)．The adverse reaction rate for the treatment group and the contrant group was respectively 21.3% and 57.3%,with significant difference(P<0.05) between two groups．Conclusion Tongluo Zhitong Decoction in the treatment of the Postherpetic Neuralgia was more advantage than Ganapentin Capsule． |
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