| 邱红美,陆建红,董长林.常见多重耐药菌感染分布及耐药性分析[J].浙江中西医结合杂志,2015,25(11): |
| 常见多重耐药菌感染分布及耐药性分析 |
| Common multidrug-resistant bacteria infection distribution and drug resistance analysis |
| 投稿时间：2015-04-24 修订日期：2015-04-24 |
| DOI： |
| 中文关键词: 多重耐药菌 耐药性 感染分布 |
| 英文关键词:multidrug-resistant bacteria drug resistance infection distribution |
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| 中文摘要: |
| 【】目的 了解我院住院病人多重耐药菌感染分布及耐药性情况,为临床有效控制多重耐药菌的感染提供有力证据。方法 采集2013年10月至2014年9月期间住院患者送检的1162株多重耐药菌,经美国BD公司Phoenix-100仪器培养鉴定并进行药敏试验,结果判断参照CLSI2012的解释标准；采用WHONET5.6软件进行统计分析。结果 1162株多重耐药菌中共分离出产ESBLs大肠埃希菌357株,金黄色葡萄球菌107株,铜绿假单胞菌276株,肺炎克雷伯菌95株,鲍曼不动杆菌209株,粪肠球菌96株,屎肠球菌34株,其中耐万古霉素金黄色葡萄球菌1株,耐万古霉素屎肠球菌3株。多重耐药菌株主要来源于痰液、中段尿、创面分泌物、全血标本。MRSA对替考拉宁、万古霉素有较好敏感性。屎肠球菌耐药率普遍高于粪肠球菌。亚胺培南和美罗培南对产ESBLs肺炎克雷伯菌和大肠埃希菌有较好敏感性,铜绿假单胞菌对氨苄西林、氨苄西林/舒巴坦、阿莫西林/克拉维酸、头孢唑林、头孢噻肟、四环素、氯霉素、复方磺胺八种药物出现普遍耐药,鲍曼不动杆菌几乎泛耐药。结论 应继续监测我院多重耐药菌的感染情况,按周期性进行整理总结,并及时制定有效干预措施,控制多重耐药菌的流行,甚至泛耐药菌的增加。 |
| 英文摘要: |
| 【】 Objective: to understand the hospital inpatient multidrug-resistant bacteria infection distribution and drug resistance, for clinical effective control of multidrug-resistant bacteria infection provide powerful evidence. Methods: collected during October 2014 to September 2013 hospitalized patients were 1162 strains of multidrug-resistant bacteria by BD company Phoenix - 100 instrument, culture identification and drug sensitive test, the result judge reference CLSI2012 interpretation standards; Using WHONET5.6 software for statistical analysis. Results: 1162 strains of multidrug-resistant bacteria separated from ESBLs 357 strains of e. coli, 95 strains of klebsiella pneumoniae,107 strains of staphylococcus aureus , 276 strains of pseudomonas aeruginosa, 209 strains of acinetobacter baumannii, 96 strains of dung enterococcus, 34strains of excrement enterococcus, including 1 strain of vancomycin resistant staphylococcus aureus, 3 strains of resistant to vancomycin excrement enterococcus. Multidrug-resistant strains from sputum, midway through the urine, wound secretion, whole blood specimens.MRSA in their stead, rather, it has good sensitivity to vancomycin.Enterococcus excrement enterococcus resistant rate is generally higher than that of dung.Imine culture south and e.faecalis for producing ESBLs pneumonia klebsiella bacteria and e. coli has good sensitivity, pseudomonas aeruginosa to ampicillin, ampicillin/shu ba jotham, amoxicillin/clavulanic acid, cefazolin, cefotaxime, tetracycline, chloramphenicol, compound sulfanilamide eight kinds of drugs of widespread drug resistance, almost generic drug resistant acinetobacter baumannii.Conclusion: should continue to monitor the hospital infection status of multidrug-resistant bacteria, according to the periodic summarize, and timely make effective interventions to control the prevalence of multdrug-resistant bacteria, and even the increase of the drug-resistant bacteria. |
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