| 翁科迪,曹铨,石钢,方益.帕瑞昔布钠超前镇痛对老年股骨转子间骨折术后镇痛及术后谵妄的影响[J].浙江中西医结合杂志,2016,26(8): |
| 帕瑞昔布钠超前镇痛对老年股骨转子间骨折术后镇痛及术后谵妄的影响 |
| Effects of preemptive analgesia with parecoxib sodium on postoperative analgesia and delirium in senile intertrochanteric fracture. |
| 投稿时间：2015-10-27 修订日期：2016-03-03 |
| DOI： |
| 中文关键词: 帕瑞昔布钠 超前镇痛 术后镇痛 术后谵妄 股骨转子间骨折 |
| 英文关键词:Parecoxib sodium Preemptive analgesia Postoperative analgesia Postoperative delirium Intertrochanteric fracture |
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| 中文摘要: |
| 目的 探讨帕瑞昔布钠超前镇痛对老年股骨转子间骨折术后镇痛及术后谵妄的影响。方法 采用回顾性分析的方法,分析58例采用手术治疗的老年股骨转子间骨折患者的临床资料,根据镇痛方式不同分为治疗组和对照组,其中治疗组30例,采用帕瑞昔布钠超前镇痛,对照组28例,采用哌替啶传统止痛。分析两组术后的镇痛效果及术后谵妄的发生率。结果 治疗组术后2,4,6,12,24,48h的疼痛视觉模拟评分法(VAS)均低于对照组,差异均有统计学意义(P＜0.05)。术后2周内治疗组的谵妄发生率为20％，对照组的谵妄发生率为50％，治疗组的谵妄发生率少于对照组,差异有统计学意义(P＜0.05)。结论 老年股骨转子间骨折术前应用帕瑞昔布钠行超前镇痛可以提高患者术后镇痛效果,降低术后谵妄的发生率,值得临床推广。 |
| 英文摘要: |
| Objective To analyze the effects of preemptive analgesia with parecoxib sodium on postoperative analgesia and delirium in senile intertrochanteric fracture. Methods To retrospective analyze the clinical data of 58 patients after senile intertrochanteric fracture operation, which was to be divided into treatment group (30 cases) and control group (28 cases) according to different analgesic methods. Patients in the treatment group received the preemptive analgesia with parecoxib sodium. Patients in the control group received the traditional analgesia with pethidine. The postoperative analgesic effects and the incidences of postoperative delirium of the two groups were compared. Results The Visual analogue scale (VAS) scores at the 2,4,6,12,24 and 48h after operation were lower in the treatment group than in the control group, there were significant differences between the 2 groups (P＜0.05). The incidence of postoperative delirium in 2 weeks after operation were 20.00％ in treatment group and 50.00％ in control group. In the treatment group,the incidence of postoperative delirium was significantly alleviated as compared with control group (P＜0.05). Conclusion The preemptive analgesia with parecoxib sodium in senile intertrochanteric fracture can improve the effect of postoperative analgesic, and reduce the incidence of postoperative delirium, is worthy of clinical promotion. |
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