| 王真.益气健脾法对COPD中重度稳定期脾肺气虚型患者症状及运动耐能的影响[J].浙江中西医结合杂志,2016,26(10): |
| 益气健脾法对COPD中重度稳定期脾肺气虚型患者症状及运动耐能的影响 |
| Effect of Supplementing Qi and strengthening spleen on the symptoms and exercise tolerance of patients with COPD in Moderate and severe stable stage of spleen deficiency syndrome |
| 投稿时间：2016-01-24 修订日期：2016-08-17 |
| DOI： |
| 中文关键词: 慢性阻塞性肺疾病稳定期，益气健脾法，临床症状，运动耐能 |
| 英文关键词:Chronic obstructive pulmonary disease Reinforcing qi to invigorate spleen yang clinical symptoms athletic ability |
| 基金项目:浙江省中医药重点研究计划（No.2010ZZ004）浙江省重大科技专项计划项目（No.2012C13017-3） |
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| 中文摘要: |
| 目的：对比慢性阻塞性肺疾病(COPD)中重度稳定期病人使用西药组联合中药安慰剂与西药合并使用益气健脾法组的不同,发现益气健脾法对患者临床症状及运动耐能的影响。方法：共收集48例患者资料,随机双盲分为试验组(24例)及对照组(24例),试验组给予沙美特罗替卡松粉吸入剂50ug/500u及益气健脾法中药,对照组给予沙美特罗替卡松粉吸入剂500ug/50ug及中药安慰剂,疗程为2个月,以中医证候积分、中医症候疗效指数、6分钟步行距离(6MWT)为观察指标。结果： ①对比两组治疗前后的中医证候积分、中医症候疗效指数方面,两组相比具有统计学意义(P<0.01),试验组较对照组更为有效。②对比两组治疗前后的六分钟步行距离,结果显示,试验组比对照组的六分钟步行距离增加量更为明显(P＜0.01)。结论：采用益气健脾法相配合西药治疗慢性阻塞性肺疾病中重度稳定期患者能更好的改善患者的临床症状及运动耐能。 |
| 英文摘要: |
| Objective: To observe the effect of tonifying qi and spleen method on clinical symptoms, athletic ability in patients of stable chronic obstructive pulmonary disease (COPD) with deficiency of lung and spleen qi. Method:Totally 48 stable COPD patients were randomly divided into an experimental group (24 cases) and a control group (24 cases). The experimental group was treated with Salmeterol/Fluticasone 50μg/500μg 1 suck twice daily and Chinese medicine of Supplementing Qi and nourishing spleen, and the control group used Salmeterol/Fluticasone 50μg/500μg 1 suck twice a day and Placebo. Treated for two months, clinical symptoms, TCM symptom index and 6 minutes walking distance(6MWD)of the groups were compared. Result：①After treatment, Compared with the clinical symptoms, TCM symptom efficacy index in the two groups, the two groups had statistical significance(P<0.01),The experimental group was more effective than the control group.②By comparing the six minutes walking distance between the two groups, The experimental group increased more than the control group. Conclusion：The patients with stable COPD who were treated by tonifying qi and spleen method could improve their clinical symptoms and athletic ability. |
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