| 邓素锦.急性脑梗死应用注射用红花黄色素联合阿加曲班对血液流变学及炎症因子的影响[J].浙江中西医结合杂志,2016,26(10): |
| 急性脑梗死应用注射用红花黄色素联合阿加曲班对血液流变学及炎症因子的影响 |
| The effect of Safflower Yellow injection combined with argatroban on hemorheology and inflammatory factors in patients with cerebral infarction |
| 投稿时间：2016-03-19 修订日期：2016-05-04 |
| DOI： |
| 中文关键词: 急性脑梗死 注射用红花黄色素 炎症因子 血液流变学 |
| 英文关键词:: Acute cerebral infarction injection safflower yellow pigment inflammatory factor hemorheology |
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| 中文摘要: |
| 【】目的 探讨注射用红花黄色素联合阿加曲班对急性脑梗死病人血液流变学及炎症因子的影响。方法 将2013年11月到2015年11月期间来我院诊治的108例急性脑梗死病人作为研究对象,并随机将其分成了治疗组(注射用红花黄色素联合阿加曲班治疗)与对照组(阿加曲班治疗),比较两组的疗效、血液流变学及炎症因子的变化情况。结果 治疗组和对照组的总有效率分别是96.36%和81.82%,治疗组的总有效率显著的高于对照组,比较差异具有显著性(P＜0.05)；治疗后,治疗组的全血高、低剪切粘度、红细胞压积、血浆高剪切粘度、纤维蛋白原含量以及血小板聚集率明显低于对照组,比较差异具有显著性(P＜0.05)；治疗后,治疗组的hs-CPR、TNF-α、IL-6以及IL-8水平显著的低于对照组,比较差异具有显著性(P＜0.05)。结论 注射用红花黄色素联合阿加曲班治疗急性脑梗死在改善血液流变学、降低炎症因子水平,提高疗效方面具有显著的优势。 |
| 英文摘要: |
| ：Objective The effect of Safflower Yellow injection combined with argatroban on hemorheology and inflammatory factors in patients with acute cerebral infarction. Methods Between November 2013 and November 2015, 108 patients with acute cerebral infarction were randomly divided into treament group (Safflower Yellow injection combined with argatroban treatment) and control group (only argatroban treatment). To compare the efficacy, the change of hemorheology and inflammatory factors for both groups. Results The tota efficiency was 96.36% and 81.82% for treatment group and control group, the treatment group was significantly higher than control group, the difference was significant (P <0.05); After treatment, p whole blood high and low shear viscosity, hematocrit, plasma high-shear viscosity, fibrinogen, and platelet aggregation for the treatment grou was significantly lower than the control group, the difference was significant (P <0.05); After treatment, hs-CPR, TNF-α, IL-6, and IL-8 levels for the treatment group were significantly lower than the the control group, the difference was significant (P <0.05). |
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