| 董亚儿,孙霞.右美托咪定对腹腔镜下子宫肌瘤切除术患者效果及应激反应和血流动力学影响研究[J].浙江中西医结合杂志,2016,26(11): |
| 右美托咪定对腹腔镜下子宫肌瘤切除术患者效果及应激反应和血流动力学影响研究 |
| Dexmedetomidine scheduled for laparoscopic myomectomy patients and the effect of the stress response and hemodynamic impact studies |
| 投稿时间:2016-05-08 修订日期:2016-05-15 |
| DOI: |
| 中文关键词: 右美托咪定 腹腔镜 子宫肌瘤切除术 效果 应激反应 血流动力学 |
| 英文关键词:dexmedetomidine given laparoscopic myomectomy effects stress reaction hemodynamics |
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| 中文摘要: |
| 目的:探讨右美托咪定对腹腔镜下子宫肌瘤切除术患者效果及应激反应和血流动力学影响。方法:选择我院于2014年10月~2015年10月期间收治的行腹腔镜下子宫肌瘤切除术患者79例,依据随机数字表法随机分为观察组40例与对照组39例。观察组静脉注射右美托咪定,对照组静脉注射等剂量生理盐水。比较两组患者拔管时间、躁动评分,不同时点应激反应和血流动力学变化。结果:两组拔管时间比较无统计学差异(P>0.05),观察组躁动评分明显低于对照组(P<0.05);观察组T1、T2、T3时点NE和Cor水平与T0时点比较无统计学差异(P>0.05);对照组T1、T2、T3时点NE和Cor水平较T0时点明显增加(P<0.05);观察组T1、T2、T3时点NE和Cor水平均明显低于同期对照组(P<0.05);观察组T2、T3时点HR和MAP比较无统计学差异(P>0.05);对照组T2、T3时点HR和MAP较T0时点明显上升(P<0.05);观察组T2、T3时点HR和MAP均明显低于同期对照组(P<0.05)。结论:右美托咪定对腹腔镜下子宫肌瘤切除术患者效果明显,对应激反应和血流动力学影响小,且可预防躁动,值得研究。 |
| 英文摘要: |
| Objective: To evaluate dexmedetomidine scheduled for laparoscopic myomectomy patients and the effect of the stress response and hemodynamic effects. Methods: A hospital in October 2014 ~ October 2015 under admitted during laparoscopic myomectomy 79 patients, were randomly divided into observation group 40 cases and the control group 39 cases. Observation group intravenous dexmedetomidine given control group dose intravenous injection of saline. There were compared extubation time, agitation rates, the stress response at different time points and hemodynamic changes. Results: two groups extubation time was no significant difference (P>0.05), agitation scale observation group was significantly lower than the control group (P<0.05); the observation group T1, T2, T3 point Cor and NE levels at T0 There was no significant difference (P>0.05); the control group T1, T2, T3 point Cor and NE levels were significantly increased (P<0.05) compared with those at T0; observation group T1, T2, T3 point Cor and NE average water significantly lower than those in the control group (P<0.05); the observation group T2, T3 point HR and MAP no significant difference (P>0.05); control group, T2, T3 point HR and MAP increased significantly compared with that at T0 (P<0.05); the observation group T2, T3 point HR and MAP were significantly lower than those in the control group (P<0.05). Conclusion: dexmedetomidine given to laparoscopic myomectomy patients obvious effect, little effect on stress reaction and hemodynamics, and can prevent restlessness, is worth studying. |
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