| 兰建萍,郑顺.认知行为干预联合阿立哌唑在改善精神分裂症患者认知功能的作用研究[J].浙江中西医结合杂志,2017,27(4): |
| 认知行为干预联合阿立哌唑在改善精神分裂症患者认知功能的作用研究 |
| The research of cognitive behavioral interventions combined with aripiprazole for improving cognitive function in schizophrenia patients |
| 投稿时间：2016-08-28 修订日期：2017-02-21 |
| DOI： |
| 中文关键词: 阿立哌唑 认知行为干预 精神分裂症 认知功能 |
| 英文关键词:aripiprazole cognitive behavioral intervention schizophrenia cognitive function |
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| 中文摘要: |
| 目的 探讨研究认知行为干预联合阿立哌唑在改善精神分裂症患者认知功能的作用效果。方法 选择2012年5月至2015年12月期间在我院精神科住院的精神分裂症患者90例作为研究对象，根据随机数字表法平均分成研究组和对照组，对照组患者给予阿立哌唑治疗，研究组患者在对照组的基础上给予认知行为干预治疗。比较分析治疗2个月后两组患者的认知功能改善情况。结果 治疗2个月后两组患者的阳性症状、阴性症状、一般病理症状和总分均较治疗前高，差异有统计学意义（P＜0.05），但组间差异没有统计学意义（P＞0.05）。研究组患者在治疗2个月后完成分类数、正确应答数、概念化水平百分数、持续性应答数等指标均明显高于对照组，持续错误数明显低于对照组，差异均有统计学意义（P＜0.05）。治疗2个月后两组患者的WMS各指标评分均明显提高，且研究组高于对照组，差异有统计学意义（P＜0.05）。结论 认知行为干预联合阿立哌唑治疗相比单纯采用阿立哌唑治疗精神分裂症患者而言在改善其认知功能方面具有明显的优势。 |
| 英文摘要: |
| Objective To study the research of cognitive behavioral interventions combined with aripiprazole for improving cognitive function in schizophrenia patients. Methods Ninety Schizophrenia patients in Department of Psychiatry were divided into study group (n=45) and control group (n=45) according to the random number table, Patients in the control group were treated with aripiprazole azole therapy and the study group were treated with cognitive behavioral intervention on the basis of the control group. The improving of cognitive function were compared between the two groups 2 months after treatment. Results Positive symptoms, negative symptoms, general symptoms and pathology scores after treated for two months were all higher than before, the difference was statistically significant (P <0.05), but the differences between the two groups were not statistically significant (P > 0.05). Two months after treated, the complete classification number, the correct response number, the percentage of conceptual level, sustained response in the study group were significant higher than the control group (P <0.05). After 2 months of treatment, the score of each index of WMS in both groups was significantly higher than before, and the study group was higher than the control group, the differences was statistically significant (P <0.05). Conclusion Comparing to taking aripiprazole medicine alone, cognitive behavioral interventions combined with aripiprazole therapy has a distinct advantage in improving their cognitive function. |
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