| 刘兰英,骆利元,朱春青,李亚平.自拟健脾养阴汤治疗文拉法辛导致的盗汗症的临床观察[J].浙江中西医结合杂志,2017,27(7): |
| 自拟健脾养阴汤治疗文拉法辛导致的盗汗症的临床观察 |
| Clinical observation on effect of JianPiYangYin decoction on night sweat caused by venlafaxine in patients with depression. |
| 投稿时间：2016-11-14 修订日期：2017-01-25 |
| DOI： |
| 中文关键词: 自拟健脾养阴汤 盗汗症 文拉法辛 |
| 英文关键词:JianPiYangYin decoction Night sweat Venlafaxine. |
| 基金项目:国家自然基金项目(No.81403502) |
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| 中文摘要: |
| 目的：观察健脾养阴汤治疗文拉法辛导致的盗汗症的临床疗效。方法：对90例使用文拉法辛治疗抑郁症后出现盗汗并中医辨证为气阴不足证的患者，随机分为研究组和对照组，研究组采用健脾养阴汤进行干预，对照组继续使用原有治疗方案，在出现盗汗后的0周、2周采用HDSS量表评估盗汗程度，观察两组在盗汗的改善情况。结果：出现盗汗后开始治疗，治疗2周后两组HDSS评分有显著性差异（P<0.01），加用中药后可以明显减少文拉法辛引起的盗汗症状，同时，加用中药后2周两组HAMD评分比较存在显著性差异（P<0.01），抑郁症状改善明显。结论：健脾养阴汤能改善文拉法辛导致的盗汗症症状，提高文拉法辛的抗抑郁效果，提高抗抑郁药依从性。 |
| 英文摘要: |
| Objective： To explore the effect of JianPiYangYin decoction on night sweat caused by venlafaxine in patients with depression.Methods： According to the principle of randomized, 90 night sweat caused by venlafaxine patients were divided in research group(n=46) treated by JianPiYangYin decoction combined with venlafaxine and control group (n=44) treated by venlafaxine. Evaluating the improvement of night sweat symptom by Hyperhidrosis Disease Severity Scale（HDSS）at the beginning of the treatment and the second week. Evaluating the the effect of antidepressant by Hamilton Depression Scale（HAMD-24）at the beginning of the treatment, the second week .Results：The scores of HDSS and HAMD-24 were both statistically significant difference between the research group and the control group after two weeks treatment(P<0.01), the severity of night sweat of the research group were significant reduced by JianPiYangYin decoction, and the the effect of antidepressant was better than the control group.Conclusion ：JianPiYangYin decoction can reduce the night sweat caused by venlafaxine, improve the effect of antidepressant and medication compliance. |
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