| 王继兴.苦碟子注射液辅助治疗急性脑梗死患者临床疗效及对患者血清炎症因子水平影响[J].浙江中西医结合杂志,2018,28(1): |
| 苦碟子注射液辅助治疗急性脑梗死患者临床疗效及对患者血清炎症因子水平影响 |
| The clinical effect and the changes of serum inflammatory factors in patients with acute cerebral infarction treated by Kudiezi injection |
| 投稿时间：2017-04-09 修订日期：2017-07-04 |
| DOI： |
| 中文关键词: 苦碟子注射液 急性脑梗死 疗效 炎症因子 |
| 英文关键词:bitter dish injection acute cerebral infarction curative effect inflammatory factor |
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| 中文摘要: |
| 目的：探讨苦碟子注射液辅助治疗急性脑梗死患者临床疗效及对患者血清炎症因子水平变化影响。方法：本组116例急性脑梗死患者选择我院神经内科2016年1月至2017年1月,按照随机数字表分为治疗组和对照组,各58例。对照组采用基础治疗,治疗组在对照组基础上结合苦碟子注射液辅助治疗。两组患者均以7d为1个治疗疗程,连续治疗2个疗程。结果：治疗组治疗总有效率(93.10%)高于对照组(75.86%)(X2=6.576,P<0.05)；两组治疗后日常生活活动能力评分增加(对照组t=11.914,治疗组t=24.427,P<0.05)；治疗组治疗后日常生活活动能力评分高于对照组(t=15.394,P<0.05)；两组治疗后血清Hcy、IL-1β、TNF-α水平降低(对照组t=13.379、9.645、13.000,治疗组t=27.461、25.275、21.519,P<0.05)；治疗组治疗后血清Hcy、IL-1β、TNF-α水平低于对照组(t=20.588、18.185、11.221,P<0.05)。 |
| 英文摘要: |
| Objective: To investigate the clinical effect and the changes of serum inflammatory factors in patients with acute cerebral infarction treated by Kudiezi injection. Methods: 116 cases of patients with acute cerebral infarction in our hospital from January 2016 to January 2017, according to random number table divided into treatment group and control group, each group of 58 cases. The control group was treated with basic treatment, and the treatment group was treated with the combination of the treatment of the Kudiezi injection and the control group. Two groups of patients with 7d for the treatment of the course of treatment, continuous treatment of 2 courses of treatment. Results: the total efficiency of the treatment group (93.10%) was higher than the control group (75.86%) (X2=6.576, P<0.05); ADL score increased after treatment in two groups (control group t=11.914, treatment group t=24.427, P<0.05); ADL scores of treatment group was higher than the control group (t=15.394, P<0.05); serum Hcy, IL-1β, TNF-α levels decreased in two groups after treatment (control group t=13.379, 9.645, 13, 25.275, 21.519, the treatment group t=27.461, P<0.05); the serum Hcy, IL-1β, TNF-α levels after treatment in the treatment group than in the control group (t =20.588, 18.185, 11.221, P<0.05). Conclusion: the clinical curative effect of the treatment of acute cerebral infarction with the aid of the tablet injection is obvious, and can reduce the serum Hcy, IL-1β, TNF-α level and further reduce the inflammatory response, which has important research significance. |
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