| 王晨晔,孙忻,丁彩飞,鲍严钟.毓麟珠方联合针刺治疗多囊卵巢综合征不孕症排卵障碍的临床研究[J].浙江中西医结合杂志,2018,28(12): |
| 毓麟珠方联合针刺治疗多囊卵巢综合征不孕症排卵障碍的临床研究 |
| Clinical Study on Yulinzhu Decoction Combined with Acupuncture in Treating Ovulation Disorder of Infertility with Polycystic Ovary Syndrome |
| 投稿时间：2018-02-24 修订日期：2018-05-09 |
| DOI： |
| 中文关键词: 毓麟珠 针刺 多囊卵巢综合征 不孕症 排卵障碍 |
| 英文关键词:YulinZhu acupuncture polycystic ovary syndrome infertility ovulation disorder |
| 基金项目:杭州市科委编号(20150733Q38) |
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| 中文摘要: |
| 目的 观察毓麟珠方联合针刺对多囊卵巢综合征不孕症排卵障碍的影响。方法 将60 例肾虚型多囊卵巢综合征不孕症患者,随机分为治疗组和对照组,每组 30 例。治疗组采用中药毓麟珠方联合针刺治疗；对照组采用氯米芬+绒促性素(HCG)治疗；两组疗程：3个月经周期。观察两组患者治疗前后治疗总体效果,排卵率,妊娠率；排卵周期子宫内膜厚度、子宫内膜形态；月经或撤退性出血第3天血清卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E2)指标变化。结果 治疗组与对照组临床总有效率比较,差异无统计学意义(P>0.05)；3个周期治疗过程中,对照组周期排卵率显著高于治疗组,差异有统计学意义(P<0.05)；治疗组妊娠率与对照组比较,差异无统计学意义(P>0.05)；两组患者排卵周期内,治疗组子宫最大内膜厚度大于对照组,差异有统计学意义(P<0.05)；治疗组A 型内膜率高于对照组,差异有统计学意义(P<0.05)；治疗前,两组LH、FSH、E2激素水平比较,差异无统计学意义(P>0.05)；治疗后治疗组和对照组LH水平均较治疗前显著下降,差异有统计学意义(P<0.05)；治疗组治疗后LH水平较对照组治疗后低,差异有统计学意义(P<0.05)；结论 毓麟珠方联合针刺可能从改善多囊卵巢综合征不孕症排卵,增加子宫内膜厚度,调整子宫内膜形态,降调节促黄体生成素等方面提高妊娠率。 |
| 英文摘要: |
| Objective: To observe the effect of Yulinzhu decoction acupuncture on ovulation disorder in infertility patients with polycystic ovary syndrome. Methods：Sixty cases of renal deficiency type polycystic ovary syndrome infertility patients were randomly divided into treatment group and control group, each group of thirty cases. The treatment group was treated with clomiphene + chorionic gonadotropin (HCG). The two groups were treated with three menstrual cycles. (FSH) and luteinizing hormone (LH) were measured before and after treatment in the two groups before and after treatment. The ovulation rate, ovulation rate, ovarian cycle endometrial thickness, endometrial morphology, ), Estradiol (E2) changes. Results ：There was no significant difference in the total effective rate between the treatment group and the control group (P> 0.05). The ovulation rate of the control group was significantly higher than that of the control group at 3 cycles (P <0.05 (P <0.05). The maximal intimal thickness of the treatment group was significantly higher than that of the control group (P <0.05). The difference between the two groups was statistically significant (P <0.05) (P <0.05). There was no significant difference in the levels of LH, FSH and E2 between the two groups before treatment (P> 0.05). The treatment group was significantly higher than that of the control group (P <0.05) (P <0.05). The level of LH in the treatment group was significantly lower than that in the control group (P <0.05), and the difference was statistically significant (P <0.05). The level of LH in the treatment group and the control group was significantly lower than that in the control group. Conclusion ：YulinZhu decoction acupuncture may improve the pregnancy rate by improving the ovulation of polycystic ovary syndrome, increasing the thickness of the endometrium, adjusting the endometrial morphology, lowering the regulation of luteinizing hormone and so on. |
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