| 金云燕.慢性肾衰竭合并急性肾损伤相关影响因素分析[J].浙江中西医结合杂志,2019,29(9): |
| 慢性肾衰竭合并急性肾损伤相关影响因素分析 |
| Analysis of related factors of chronic renal failure complicated with acute renal injuryJin Yunyan Zhang Xiaohui Lou Hongqing Zhou Sangjin Zhou Yanxue Ye Linfeng Jin hangChao the Central Hospital of Yiwu City Department of Nephrology, 322000 |
| 投稿时间:2018-12-29 修订日期:2019-01-15 |
| DOI: |
| 中文关键词: 慢性肾衰竭 急性肾损伤 影响因素 |
| 英文关键词:chronic renal failure acute renal injury influencing factors |
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| 中文摘要: |
| 目的:探讨慢性肾衰竭合并急性肾损伤相关影响因素。方法:选择我院于2016年1月至2018年9月期间收治的慢性肾衰竭患者200例作为研究对象,合并急性肾损伤71例。采用多因素分析影响慢性肾衰竭合并急性肾损伤危险因素,收集患者临床资料,包括性别、年龄、体重指数、合并高血压、合并糖尿病、机械通气、急性感染、肾毒性药物、血管活性药物、低血容量。结果:经单因素分析表明,不同性别、体重指数、高血压和糖尿病合并急性肾损伤发生率比较无统计学意义(P>0.05);年龄>50岁合并急性肾损伤发生率高于年龄≤50岁,机械通气合并急性肾损伤发生率高于无机械通气,急性感染合并急性肾损伤发生率高于无急性感染,肾毒性药物合并急性肾损伤发生率高于无肾毒性药物,血管活性药物合并急性肾损伤发生率高于无血管活性物质,具有统计学意义(P<0.05)。将上述单因素分析具有统计学意义的纳入多因素分析表明,年龄>50岁、机械通气和急性感染为影响慢性肾衰竭合并急性肾损伤危险因素。结论:慢性肾衰竭合并急性肾损伤受多因素影响,其中年龄、机械通气和急性感染为其危险因素。 |
| 英文摘要: |
| Objective: To explore the related factors of chronic renal failure with acute renal injury. Methods: The 200 patients with chronic renal failure admitted to our hospital from January 2016 to September 2018 were selected as the study subjects, 71 patients with acute renal injury. Multivariate analysis was used to analyze the risk factors of chronic renal failure with acute renal injury. Clinical data of patients were collected, including gender, age, body mass index, hypertension, diabetes mellitus, mechanical ventilation, acute infection, nephrotoxic drugs, vasoactive drugs and hypovolemia. Results: Univariate analysis showed that there was no significant difference in the incidence of acute kidney injury between different gender, body mass index, hypertension and diabetes mellitus (P>0.05); the incidence of acute kidney injury in patients aged over 50 years was higher than that in patients aged less than 50 years, the incidence of mechanical ventilation combined with acute kidney injury was higher than that without mechanical ventilation, and the incidence of acute infection combined with acute kidney injury was higher than that without acute sensation. The incidence of nephrotoxic drugs combined with acute renal injury was higher than that of non-nephrotoxic drugs, and the incidence of vasoactive drugs combined with acute renal injury was higher than that of non-vasoactive substances (P<0.05). Including the above univariate analysis into multivariate analysis showed that age > 50 years old, mechanical ventilation and acute infection were risk factors for chronic renal failure complicated with acute renal injury. Conclusion: Chronic renal failure complicated with acute renal injury is affected by many factors, among which age, mechanical ventilation and acute infection are the risk factors. |
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