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张丽霞,陈浩波,胡慧娟,王美霞.中药周期疗法结合中医情志疗法治疗肾虚肝郁型卵巢早衰的临床疗效观察[J].浙江中西医结合杂志,2021,31(12):
中药周期疗法结合中医情志疗法治疗肾虚肝郁型卵巢早衰的临床疗效观察
投稿时间:2021-03-01  修订日期:2021-09-29
DOI:
中文关键词:  卵巢早衰  中药周期疗法  中医情志疗法  临床疗效
英文关键词:Premature ovarian failure  Periodic Chinese medicine therapy  Emotion therapy of Traditional Chinese medicine  Clinical curative effect
基金项目:
作者单位E-mail
张丽霞* 浙江中医药大学附属温州市中西医结合医院 1294654187@qq.com 
陈浩波 浙江中医药大学附属温州市中西医结合医院  
胡慧娟 浙江中医药大学附属温州市中西医结合医院  
王美霞 浙江中医药大学附属温州市中西医结合医院  
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中文摘要:
      摘要 目的 探讨中药周期疗法联合中医情志疗法治疗肾虚肝郁型卵巢早衰的临床治疗效果。方法 将2017年8月—2020年2月就诊于我院并符合课题诊断标准的120例卵巢早衰患者作为研究对象,按随机数字表法分为中药组、西药组、治疗组三组,每组各40例;中药组患者按照月经期、经后期、经间期、经前期四期予以中药进行治疗;西药组患者予以补佳乐联合地屈孕酮行激素替代治疗,治疗组患者采用中药周期疗法与中医情志疗法相结合的方式治疗;三组的治疗时间均为6个月,随访2个月,比较三组患者治疗前及治疗后的中医症候积分、血性激素的变化和临床疗效。结果 治疗后,三组总有效率分别为治疗组总有效率为72.5%;中药组总有效率为67.5%;西药组总有效率为75%。三组总有效率无明显差异(P>0.05)。在改善中医症候积分上,治疗组效果最佳,中药组次之,治疗组及中药组与西药组比较,差异有统计学意义(P<0.05)。在降低FSH水平,提高E2水平方面,治疗组、中药组的效果不及西药组(P<0.05)。结论 中药周期疗法联合中医情志疗法治疗肾虚肝郁型卵巢早衰的临床效果肯定,尤其在改善中医症候积分上,具有在临床中推广实施的价值。
英文摘要:
      Summary Objective to explore the clinical effect of periodical therapy of traditional Chinese medicine combined with emotional therapy of traditional Chinese medicine on premature ovarian failure (POF) of kidney deficiency and liver depression. Methods In this study, a total of 120 patients with premature ovarian failure who visited our hospital from August 2017 to February 2020 and met the diagnostic criteria of the study were selected as the research objects. According to the random number table method, they were divided into three groups: the Chinese medicine group, the Western medicine group and the treatment group, with 40 cases in each group. Patients in the TCM group were treated with TCM according to the menstrual period, the later menstrual period, the intermenstrual period and the early menstrual period. Patients in the western medicine group were treated with bujiale combined with didroprogesterone for hormone replacement therapy. Patients in the treatment group were treated with periodic therapy of Chinese medicine combined with emotion therapy of Chinese medicine. The duration of treatment in the three groups was 6 months. To compare the scores of TCM syndromes, Changes in blood hormones and clinical efficacy of three groups of patients before and after treatment. Results After treatment, the total effective rate was 72.5% in the treatment group, 77.5% in the Western medicine group and 65% in the Traditional Chinese medicine group. The total effective rate was comparable between the treatment group and the western medicine group (P > 0.05). In terms of improving the score of TCM syndromes, the treatment group had better effect than the Western medicine group and the Chinese medicine group, and the difference was statistically significant (P < 0.05). In terms of decreasing FSH level and increasing E2 level, the effect of the treatment group and the Chinese medicine group was not as good as that of the Western medicine group (P < 0.05). Conclusion The clinical effect of TCM periodic therapy combined with TCM emotion therapy in the treatment of kidney deficiency, liver depression and premature ovarian failure is definite, especially in the improvement of TCM syndrome score, and has the value of popularizing and carrying out in clinical practice. Keywords Premature ovarian failure; Periodic Chinese medicine therapy; Emotion therapy of Traditional Chinese medicine; Clinical curative effect
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