| 高泳林.氟康唑联合自制中药含漱方治疗老年口腔念珠菌病30例[J].浙江中西医结合杂志,2021,31(8): |
| 氟康唑联合自制中药含漱方治疗老年口腔念珠菌病30例 |
| Fluconazole combined with homemade Chinese medicine containing gargle prescription?for 30 cases of elderly patients with oral candidiasis |
| 投稿时间：2021-03-31 修订日期：2021-06-08 |
| DOI： |
| 中文关键词: 口腔念珠菌病 氟康唑 中药含漱 |
| 英文关键词:Oral candidiasis Fluconazole Chinese herbal gargle |
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| 中文摘要: |
| 目的 探讨中西医联合治疗对于老年口腔念珠菌的临床疗效。方法 选择2020年5月至2020年12月在杭州市西湖区中西医结合医院口腔科及住院病房收治的老年口腔念珠菌病患者共60例，依据临床治疗方法将其分为对照组和实验组，上述患者以14天为一个疗程，并对两组患者基本资料、临床伴发症状、不良反应发生率及临床治疗效果进行比较。结果 两组基本资料比对无统计学意义；治疗前口干、疼痛、红斑病损评分在两组患者间比对均无统计学意义（P＞0.05）；治疗后口干、疼痛、红斑病损评分均较治疗前降低，且两组比较差异均有统计学意义（P＜0.05）；治疗后口干、疼痛和红斑病损评分实验组均低于对照组，差异具有统计学意义（P＜0.05）；实验组不良反应总发生率低于对照组，差异具有统计学意义（P＜0.05）；两组间治疗无效率、有效率及总有效率比对无统计学意义，但显效率实验组高于对照组，差异具有统计学意义（P＜0.05）。结论 老年人口腔念珠菌病常规西医治疗效果不如中西医联合治疗，中西医联合治疗治疗期间的不良反应（恶心，呕吐，腹泻等）率更低，治疗显效率、有效率和总有效率更高，整体效果比较理想，可以进行临床应用。 |
| 英文摘要: |
| Objective To explore the clinical effect of combined treatment of traditional Chinese and western medicine on the elderly oral Candida. Methods A total of 60 elderly patients with oral candidiasis who were admitted to the Department of Stomatology and inpatient wards of the Xihu District Hospital of Integrated Traditional Chinese and Western Medicine in Hangzhou from May, 2020 to December, 2020 were divided into a control group and an experimental group based on clinical treatment methods. The above-mentioned patients took 14 days as a course of treatment, and the basic data, clinical complications, incidence of adverse reactions and clinical treatment effects of the two groups of patients were compared. Results The basic data of the two groups were not statistically significant; the scores of dry mouth, pain, and erythema before treatment were not statistically significant between the two groups (P>0.05); dry mouth, pain,
erythema after treatment Damage scores were lower than before treatment, and the difference between the two groups was statistically significant (P<0.05); dry mouth, pain and erythema lesions scores in the experimental group were lower than those in the control group after treatment, and the difference was statistically significant (P ＜0.05),The total incidence of adverse reactions in the experimental group was lower than that in the control group, and the difference was statistically significant (P＜0.05); The comparison of treatment inefficiency, effective rate and
total effective rate between the two groups was not statistically significant, but significant efficiency The experimental group was higher than the control group, and the difference was statistically significant (P<0.05). Conclusion The conventional western medicine treatment of oral candidiasis in the elderly is not as effective as the combined treatment of traditional Chinese and western medicine. The rate of adverse reactions (nausea, vomiting, diarrhea, etc.) during combined treatment of traditional Chinese and western medicine is lower, and the effective,
effective and total effective rate of treatment is higher.The overall effect is relatively ideal and can be used in clinical applications. |
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