| 杨笑笑,颜亚丽,阮晨金.吸烟和术前戒烟时间与肺癌患者胸腔镜术后肺部并发症之间的关系研究[J].浙江中西医结合杂志,2021,31(12): |
| 吸烟和术前戒烟时间与肺癌患者胸腔镜术后肺部并发症之间的关系研究 |
| The relationship between smoking and time to quit smoking before surgery and pulmonary complications after thoracoscopic surgery in patients with lung cancer |
| 投稿时间：2021-04-27 修订日期：2021-11-29 |
| DOI： |
| 中文关键词: 肺癌 电视胸腔镜手术 术后肺部并发症 戒烟时间 |
| 英文关键词:Lung cancer, video-assisted thoracoscopic surgery, postoperative pulmonary complications, quit smoking duration |
| 基金项目: |
|
| 摘要点击次数: 913 |
| 全文下载次数: 6 |
| 中文摘要: |
| 目的：考察吸烟和术前戒烟时间与肺癌患者电视胸腔镜手术(VATS)术后肺部并发症之间的关系。方法：对2011年4月至2020年10月在台州市中心医院通过VATS进行肺叶或肺段切除术的1751例原发性肺癌患者的病历资料进行回顾性分析。采集患者的人口学、临床和术前吸烟情况数据。考察总体样本和吸烟者样本中术后肺部并发症发生率及其相关的因素，并依据术前戒烟时间对肺部并发症的发生率进行分层分析。结果：共纳入1751例患者的病例资料，其中936例(53.4%)有吸烟史。多因素Logistic分析显示，在总体样本中，有吸烟史[OR(95CI%): 3.31(1.39–7.72), P=0.007)]是术后肺部并发症的独立危险因素。吸烟者样本中，戒烟时间＜2个月的患者比戒烟时间＞2个月患者发生术后肺部并发症的风险增加了1倍[OR(95CI%): 2.05 (1.04–4.37), P= 0.043]。戒烟时间＜2个月的患者比非吸烟者增加了9倍[OR(95CI%): 10.78(4.02-28.94)，P < 0.001]，戒烟＞2个月的吸烟者发生肺部并发症的风险比非吸烟者增加了3倍[OR(95CI%): 4.85(2.13-11.02) ,P < 0.001]。结论：有吸烟史和术前戒烟时间与肺癌VATS肺叶切除术和肺段切除术后肺部并发症的发生率独立相关。为降低术后肺部并发症风险，建议术前至少戒烟2个月。 |
| 英文摘要: |
| Objective: To investigate the relationship between smoking and time to quit smoking before surgery and pulmonary complications after VATS in patients with lung cancer. Methods: The medical records of 1751 patients with primary lung cancer who underwent lobotomy or segmental resection via VATS in Taizhou Central Hospital from April 2011 to October 2020 were retrospectively analyzed. Demographic, clinical and preoperative smoking data were collected. The incidence of postoperative pulmonary complications and related factors in both the population sample and the smokers sample were examined, and the incidence of pulmonary complications was stratified according to the preoperative time to quit smoking. Results: A total of 1751 patients were included, of whom 936 (53.4%) had a smoking history. Multivariate Logistic analysis showed that smoking history [OR (95CI%): 3.31(1.39-7.72), P=0.007)] was an independent risk factor for postoperative pulmonary complications in the total sample. In the sample of smokers, the risk of postoperative pulmonary complications was doubled in those who had quit smoking for less than 2 months compared with those who had quit smoking for > 2 months [OR(95CI%): 2.05 (1.04-4.37), P= 0.043].Patients who had quit smoking for less than 2 months were nine times more likely than nonsmokers [OR(95CI%): 10.78(4.02-28.94), P＜0.001], and smokers who had quit > for 2 months were three times more likely than nonsmokers to develop pulmonary complications [OR(95CI%):4.85(2.13-11.02), P＜0.001].Conclusions: Smoking history and the preoperative period of abstaining were independently associated with the incidence of pulmonary complications after VATS lobectomy and segemectomy for lung cancer. To reduce the risk of postoperative pulmonary complications, a preoperative smoking cessation period of at least 2 months is preferred. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
