| 陈颖聪,刘妍妍,赵煜成,马红珍.感染相关急性肾损伤的临床特点及预后分析[J].浙江中西医结合杂志,2022,32(4): |
| 感染相关急性肾损伤的临床特点及预后分析 |
| Clinical features and prognostic analysis of infection-related acute kidney injury |
| 投稿时间：2021-09-20 修订日期：2022-03-20 |
| DOI： |
| 中文关键词: 感染 急性肾损伤 脓毒症 预后 |
| 英文关键词:Infection AKI Sepsis Prognosis |
| 基金项目: |
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| 中文摘要: |
| 目的：分析住院患者感染相关急性肾损伤（AKI）的临床特征及影响其预后的危险因素，为临床防治感染相关AKI提供依据。方法：通过收集2018年12月-2020年12月于浙江省中医院住院患者的肾功能检查结果，筛检出AKI患者，进行病史复习，回顾性分析感染相关AKI的临床特征及分布特点；Logistic 回归分析影响感染相关AKI患者预后的危险因素。结果：观察期间共纳入感染相关AKI患者71例。患者男女患病比例2.74:1。感染部位包括泌尿道感染18例、腹腔感染15例、肺部感染31例、皮肤软组织感染1例、牙周感染1例，导管相关感染3例，不明原因血流感染2例。其中合并脓毒症者共38例（53.5%）。AKI 1期10例（14.1%），2期26例（36.6%），3期35例（49.3%）。所有纳入研究的患者中，好转出院32例（45.1%），死亡20例（28.2%），自动出院19例（26.8%）。Logistic 回归分析提示脓毒症、恶性肿瘤是感染相关AKI预后可能的独立危险因素。结论：感染是AKI的主要诱因之一，主要感染部位为肺部感染，临床上感染相关AKI的发病以老年、男性居多。脓毒症、恶性肿瘤是影响患者预后的独立危险因素。 |
| 英文摘要: |
| Objective: To analyze the clinical characteristics of infection-related AKI in hospitalized patients and the risk factors that affect their prognosis, so as to provide evidence for the clinical prevention and treatment of infection-related AKI. Methods: By collecting the renal function examination results of hospitalized patients in Zhejiang Provincial Hospital of Traditional Chinese Medicine from December 2018 to December 2020, screening patients with AKI, reviewing the medical history, and retrospectively analyzing the clinical characteristics and distribution characteristics of infection-related AKI; Logistic Regression analysis of risk factors affecting the prognosis of patients with infection-related AKI. Results: A total of 71 patients with infection-related AKI were included during the observation period. The ratio of male to female patients was 2.74:1. The infection sites included 18 cases of urinary tract infection, 15 cases of abdominal cavity infection, 31 cases of lung infection, 1 case of skin and soft tissue infection, 1 case of periodontal infection, 3 cases of catheter-related infection, and 2 cases of bloodstream infection of unknown cause. There were 38 cases (53.5%) with sepsis. There were 10 cases (14.1%) in stage 1 of AKI, 26 cases (36.6%) in stage 2 and 35 cases (49.3%) in stage 3 AKI. Among all patients included in the study, 32 patients (45.1%) got better and were discharged, 20 patients died (28.2%), and 29 patients (26.8%) were discharged automatically. Logistic regression analysis suggests that sepsis and malignant tumors are possible independent risk factors for the prognosis of infection-related AKI. Conclusion: Infection is one of the main causes of AKI. The main site of infection is pulmonary infection. Clinically, the incidence of infection-related AKI is mostly in the elderly and men. Sepsis and malignant tumors are independent risk factors that affect the prognosis of patients. |
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