| 王黎丽,严雷,李华涛.康复新液对儿童烧烫伤创面修复效果观察[J].浙江中西医结合杂志,2022,32(11): |
| 康复新液对儿童烧烫伤创面修复效果观察 |
| Observation on the effect of Kangfuxin liquid on repairing children"s burns and scalds |
| 投稿时间：2021-11-05 修订日期：2022-03-24 |
| DOI： |
| 中文关键词: 儿童烧烫伤 康复新液 磺胺嘧啶银 炎性因子 |
| 英文关键词:Burns and scalds in children Kangfu Xinye Silver sulfadiazine Inflammatory factors |
| 基金项目: |
|
| 摘要点击次数: 454 |
| 全文下载次数: 7 |
| 中文摘要: |
| 目的 观察康复新液对儿童烧烫伤创面修复的治疗效果。方法 选择2018年5月-2021年5月医院接收的80例烧烫伤患儿为研究对象，采用随机数字表法分为两组，各40例。常规清创基础上，对照组用磺胺嘧啶银治疗，在此基础上观察组采用康复新液治疗，两组连续治疗2周。比较两组治疗前，治疗2周的中医证候评分、炎症因子[白细胞介素-6（IL-6）、白细胞介素-7（IL-7）]水平及细胞生长因子[血管内皮生长因子（VEGF）、转化生长因子-β1（TCF-β1）]水平；比较两组创面愈合时间及瘢痕情况。结果 治疗2周，两组中医证候评分低于治疗前，且观察组低于对照组，差异有统计学意义（P＜0.05）；治疗2周，两组患儿血清IL-6、IL-7均低于治疗前，血清VEGF和TCF-β1水平高于治疗前；且观察组IL-6、IL-7水平低于对照组，观察组VEGF和TCF-β1水平高于对照组，差异有统计学意义(P＜0.05 )；观察组创面愈合时间比对照组短，Vss评分比对照组低，差异有统计学意义（P＜0.05）。结论 康复新液可有效减轻烧烫伤患儿创面炎症，促进新生血管生成，缩短创面愈合时间，改善瘢痕情况，提高创面修复效果。 |
| 英文摘要: |
| Objective Observe the therapeutic effect of Kangfuxin liquid on children's burn wound repair. Methods Eighty children with burns and scalds received by the hospital from May 2018 to May 2021 were selected as the research objects, and they were divided into two groups using a random number table method, with 40 cases in each group. On the basis of routine debridement, the control group was treated with silver sulfadiazine, and the observation group was treated with Kangfuxin liquid on this basis. The two groups were treated for 2 weeks continuously. The scores of TCM syndromes, inflammatory factors [interleukin-6 (IL-6), interleukin-7 (IL-7)] levels and cell growth factor [vascular endothelial growth factor] were compared between the two groups before treatment for 2 weeks. (VEGF), transforming growth factor-β1 (TCF-β1)] levels; compare the wound healing time and scar situation between the two groups. Results After 2 weeks of treatment, the scores of TCM syndromes in the two groups were lower than before treatment, and the observation group was lower than the control group, the difference was statistically significant (P＜0.05); After 2 weeks of treatment, the serum IL-6 and IL-7 levels of the two groups of children were lower than before treatment, and the serum VEGF and TCF-β1 levels were higher than before treatment; and the levels of IL-6 and IL-7 in the observation group were lower than those in the control group. The levels of VEGF and TCF-β1 in the observation group were higher than those in the control group, and the difference was statistically significant (P＜0.05); the wound healing time of the observation group was shorter than that of the control group, and the Vss score was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion Kangfuxin liquid can effectively reduce the inflammation of the wound in children with burns and scalds, promote the formation of new blood vessels, shorten the healing time of the wound, improve the scar condition, and improve the effect of wound repair. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
