| 高永博,洪滔.伴牙龈炎龈缘龋治疗前后龈沟液内AST、EA、COL-Ⅱ的变化[J].浙江中西医结合杂志,2023,33(1): |
| 伴牙龈炎龈缘龋治疗前后龈沟液内AST、EA、COL-Ⅱ的变化 |
| Changes of AST, EA and COL-Ⅱ in gingival crevicular fluid before and after two kinds of ?treatment |
| 投稿时间：2021-12-16 修订日期：2022-08-24 |
| DOI： |
| 中文关键词: 龈沟液，AST，EA，COL-Ⅱ |
| 英文关键词:gingival crevicular fluid, AST, EA, COL-Ⅱ |
| 基金项目:杭州市卫生科技计划(一般)项目(2017A42) |
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| 中文摘要: |
| 目的: 比较伴慢性牙龈炎颊侧颈部龈缘龋患者牙龈炎全口洁治前后及龋损修复前后龈沟液内三种酶AST、EA、COL-Ⅱ的变化。方法:伴慢性牙龈炎颊侧颈部龈缘龋患者14例，患牙172颗，分别收集患者全口洁治前、全口洁治后一周（即Z350修复前）、Z350修复后一周龈沟液。检测龈沟液内三种酶AST、EA、COL-Ⅱ。结果:牙龈炎全口洁治后龈沟液内AST、EA含量低于治疗前，差异有显著性[（1378.36±214.69)比(2032.77±622.89)，(0.83±0.21)比(1.71±0.85)，P<0.05]；牙龈炎全口洁治后COL-Ⅱ含量较治疗前降低，差异无显著性[（819.34±265.81)比(1013.6±562.26)，P>0.05]。Z350修复后一周龈沟液三种酶AST、EA、COL-Ⅱ含量稍降低,差异无显著性[(1121.89±340.41)比(1378.36±214.69)，(0.74±0.13）比（0.83±0.21),(774.43±175.06)比(819.34±265.81),P>0.05]。结论: 牙龈炎症早期龈沟液内AST、EA增高，COL-Ⅱ变化不明显。Z350对牙龈组织刺激性小，组织相容性好，可以应用于龈下型牙体缺损修复。 |
| 英文摘要: |
| Objective: To compare the changes of AST, EA and COL-Ⅱin gingival crevicular fluid before and one week after supragingival scaling and resin filling in subgingival caries with chronic gingivitis.Methods: Gingival crevicular fluid was collected from 172 subgingival caries teeth of 14 patients with chronic gingivitis immediately and one week after supragingival scaling and another one week after Z350 nano resin repairing. The AST, EA and COL-Ⅱwere measured. Results: AST and EA contented in gingival crevicular fluid were significantly lower than prior treatment [（1378.36±214.69)vs(2032.77±622.89)，(0.83±0.21)vs(1.71±0.85)，P<0.05]. The content of COL-Ⅱwas lower than before the supragingival scaling, and there was no significant difference [（819.34±265.81)vs(1013.6±562.26)，P >0.05]. The contents of the three enzymes (AST、EA、COL-Ⅱ) decreased slightly, but there was no significant difference in statistical tests[(1121.89±340.41)vs(1378.36±214.69)，(0.74±0.13)vs
(0.83±0.21),(774.43±175.06)vs(819.34±265.81),P>0.05].Conclusion: In the early stage of gingival inflammation, AST and EA in gingival crevicular fluid increased, but the change of COL-Ⅱ was not obvious.Z350 had good histocompatibility and security on gingival tissues and so it could be used for repairing subgingival tooth defects. |
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