| 吕倩,张利.醒脑开窍针法联合经颅直流电刺激对慢性意识障碍患者促醒作用的临床疗效观测[J].浙江中西医结合杂志,2022,32(9): |
| 醒脑开窍针法联合经颅直流电刺激对慢性意识障碍患者促醒作用的临床疗效观测 |
| Observation on the clinical effect of Xingnao Kaiqiao acupuncture combined with transcranial direct current stimulation on awakening patients with prolonged consciousness disorder |
| 投稿时间：2021-12-16 修订日期：2022-06-29 |
| DOI： |
| 中文关键词: 经颅直流电刺激 醒脑开窍针 针灸 慢性意识障碍 |
| 英文关键词:transcranial direct current stimulation Xingnaokaiqiao Acupuncture Acupuncture prolonged disorders of consciousness |
| 基金项目:浙江省中医药科技计划项目 |
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| 中文摘要: |
| [摘要] 目的 探讨醒脑开窍针法联合经颅直流电刺激（transcranial direct current stimulation,tDCS）对慢性意识障碍（prolonged disorders of consciousness,pDoC）患者促醒作用的临床疗效。方法 选取浙江省人民医院2020年1月至2021年1月收治的pDoC患者60例，随机分成tDCS组、针刺组和联合组，各20例。分别给予tDCS、醒脑开窍针刺、tDCS联合醒脑开窍针刺治疗。1次/天，5 次/周，持续治疗4周。治疗前后使用修订的JFK昏迷恢复量表（CRS-R）和格拉斯哥昏迷量表（GCS）对受试者进行评定，3个月后再进行格拉斯哥预后评分量表（GOS）评定，并监测连续脑电功能，计算平均振幅整合脑电图（aEEG），比较3组临床疗效。结果 治疗后三组CRS-R、GCS、GOS评分及aEEG分级差异有统计学意义(P<0.05), 且治疗后评分联合组优于tDCS组和针刺组；联合组昏迷程度减轻明显优于针刺组和tDCS组，差异有统计学意义（P<0.05）。结论 联合组治疗效果明显优于单独tDCS及针刺治疗，可作为治疗pDoC联合疗法用于临床推广。 |
| 英文摘要: |
| [Abstract] Objective To study the clinical efficacy of Xingnao Kaiqiao acupuncture combined with Transcranial direct current stimulation（tDCS）treatment in promoting the recovery of prolonged consciousness in patients with impaired consciousness（pDoC）.Methods A total of 60 patients with pDoC in Zhejiang Provincial People's Hospital were selected.Patients with pDoC randomly divided into three groups：20 cases the acupuncture group, which undergone the Xingnao Kaiqiao acupuncture treatment ;20 cases the tDCS group,which undergone the tDCS treatment ;20 cases in combined group,which undergone Xingnao Kaiqiao acupuncture treatment and tDCS treatment.
All patients were treated one time per day, 5 days a week, and the treatment last 4 weeks. The revised JFK Coma Recovery Scale (CRS-R), Glasgow Coma Scale (GCS) and Glasgow Outcome Score Scale (GOS) were used to evaluate the subjects, and the clinical efficacy of the three groups before and after treatment. Continuous cerebral fu-
nction monitor was used to calculate average amplitude-integrated electroencephalogr-
aphy (aEEG) to analysis brain activity. Results After 4 weeks of the treatment, there were more improvement of CRS-R、GCS、GOS scores and electroencephalography ( EEG) grading in combined group than in tDCS group and in acupuncture group (P<0.05). And the score after treatment in the combined group is better than the tDCS group than the acupuncture group. The degree of coma in the combined group was significantly better than that in the acupuncture group and the tDCS group, and the difference was statistically significant (P<0.05). Conclusion The therapeutic effect of the combined group is significantly better than that of tDCS and acupuncture alone, and can be used for clinical promotion. |
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