| 郑约楠,邵国建,马飞驹,郑谊谊.血液透析患者钙镁比值与心脏瓣膜钙化的关系[J].浙江中西医结合杂志,2022,32(6): |
| 血液透析患者钙镁比值与心脏瓣膜钙化的关系 |
| Relationship between serum calcium/magnesium ratio with cardiovalvular calcification in hemodialysis patients |
| 投稿时间：2021-12-24 修订日期：2022-05-06 |
| DOI： |
| 中文关键词: 血液透析 瓣膜钙化 钙镁比值 |
| 英文关键词:Hemodialysis Cardiac Valve Calcification calcium/magnesium ratio |
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| 中文摘要: |
| 目的 研究维持性血液透析（Maintenance Hemodialysis MHD）患者心脏瓣膜钙化（Cardiac Valve Calcification,CVC）的影响因素。 方法 研究对象为我院血液透析中心行维持性血液透析治疗的159例患者，收集患者的一般资料和实验室结果，经胸超声心动图（Transthoracic Echocardiogram，TEE）测定心脏瓣膜钙化情况，分析MHD患者CVC钙化的影响因素。结果 钙化组和无钙化组间年龄、透析龄、高血压病史、血小板计数、血肌酐、血磷、血镁、钙镁比值、白蛋白水平有统计学意义（P＜ 0.05）。二元Logistic回归分析显示，高龄、长透析龄、高磷和高钙镁比值是CVC的危险因素。 结论 高钙镁比值是CVC的独立危险因素，可增加MHD患者CVC的发生。 |
| 英文摘要: |
| Objective Exploring the influencing factors of cardiac valve calcification (CVC) in hemodialysis patients. Methods 159 patients with chronic kidney disease on regular hemodialysis (HD) were recruited into this study in our center. Demographic and clinical data of selected patients were collected. Quantification of Cardiovalvular calcification (CVC) was determined by Transthoracic Echocardiogram(TEE).Analyzing the influencing factors in MHD patients with CVC. Results Patients were divided into calcification group and non-calcification group according to their TEE. There were significant differences in the distribution of the age, dialysis phosphorus, history of hypertension, platelet count, serum creatinine,serum phosphorus, serum magnesium, calcium/magnesium ratio, albumin among two groups (P＜0.05) . The independent risk factors of CVC were aging, Long dialysis phosphorus,high level of phosphorus and high level of calcium/magnesium ratio in MHD patients by using binary logistic regression.Conclusions High level of calcium/magnesium ratio is the risk factor of CVC, and can increase the occurrence of CVC in MHD patients. |
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