| 程申,李岚,王利玲,陈娟.毛支饮辅助治疗小儿呼吸道合胞病毒感染的毛细支气管炎80例临床观察[J].浙江中西医结合杂志,2022,32(7): |
| 毛支饮辅助治疗小儿呼吸道合胞病毒感染的毛细支气管炎80例临床观察 |
| Clinical Observation on 80 Cases of Children's Respiratory Syncytial Virus Infected Bronchiolitis Treated with Maozhi Decoction |
| 投稿时间：2022-01-10 修订日期：2022-03-13 |
| DOI： |
| 中文关键词: 呼吸道合胞病毒感染 小儿 毛支饮 中西医结合 临床观察 |
| 英文关键词:Respiratory syncytial virus infection children Maozhiyin integrated traditional Chinese and Western medicine clinical observation |
| 基金项目:浙江省中医药科技计划科研基金项目（2019ZB042） |
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| 中文摘要: |
| 目的 观察毛支饮辅助治疗毛细支气管炎的临床疗效。方法 选取2018年09月至2020年09月浙江省中医院儿科门诊及住院就诊的,呼吸道合胞病毒抗原阳性的毛细支气管炎患儿160例,采用电脑随机数字表法分为对照组和治疗组,各80例。其中,对照组予沙丁胺醇+异丙托溴铵+布地奈德混悬液雾化治疗,治疗组在对照组治疗的基础上加用毛支饮,2组均连续治疗1周,观察2周,并随访1年,统计2组的临床疗效,治疗前后中医症候积分改变情况。结果 治疗组总有效率为93.8%(75/80),明显高于对照组的75%(60/80),2组比较,差异有统计学意义( P＜0．05) 。治疗组喘憋消失时间和肺部啰音消失时间分别为(2.09±1.14)d、(3.29±1.47),均短于对照组的(2.80±1.24)d、(4.23±1.74)d,2组比较,差异有统计学意义(P＜0．01)。治疗前,2组年龄、咳嗽、喘憋等症状积分比较,差异均无统计学意义( P＞0．05) ,具有可比性。治疗后,2 组上述中医症状积分均降低( P＜0．05) ,且治疗组降低更显著,差异有统计学意义( P＜0．05) 。结论 毛支饮辅助治疗小儿毛细支气管炎,可显著改善小儿中医症状积分,缩短咳嗽、喘息、喘憋、肺部湿啰音吸收时间,值得临床广泛推广应用。 |
| 英文摘要: |
| Objective To observe the clinical effect of Maozhi Decoction in adjuvant treatment of bronchiolitis. Methods From September 2018 to September 2020, 160 children with bronchiolitis who were positive for respiratory syncytial virus antigen in the pediatric outpatient clinic and inpatient treatment of Zhejiang Provincial Hospital of Traditional Chinese Medicine were selected and divided into the control group and the treatment group by computer random number table method. , 80 cases each. Among them, the control group was given salbutamol + ipratropium bromide + budesonide suspension atomization treatment, the treatment group was given Maozhi Decoction on the basis of the treatment of the control group, both groups were treated continuously for 1 week, and the patients were observed for 2 weeks. The patients were followed up for 1 year, and the clinical efficacy of the two groups and the changes of TCM symptom scores before and after treatment were counted. Results The total effective rate in the treatment group was 93.8% (75/80), which was significantly higher than 75% (60/80) in the control group, and the difference was statistically significant (P<0.05). The disappearance time of wheezing and pulmonary rales in the treatment group were (2.09±1.14) d and (3.29±1.47) d, respectively, which were shorter than (2.80±1.24) d and (4.23±1.74) d in the control group. The difference was statistically significant (P<0.01). Before treatment, there were no significant differences in age, cough, wheezing and other symptom scores between the two groups (P>0.05), which were comparable. After treatment, the above-mentioned TCM symptom scores in both groups were decreased (P<0.05), and the decrease in the treatment group was more significant, and the difference was statistically significant (P<0.05). Conclusion Maozhiyin in the adjuvant treatment of children with bronchiolitis can significantly improve the TCM symptom score of children and shorten the absorption time of cough, wheezing, wheezing and pulmonary rales, which is worthy of widespread clinical application. |
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