| 张丽.老年2型糖尿病住院患者认知衰弱的影响因素分析[J].浙江中西医结合杂志,2023,33(3): |
| 老年2型糖尿病住院患者认知衰弱的影响因素分析 |
| Analysis of related factors of cognitive decline in elderly patients with type 2 diabetes mellitus |
| 投稿时间：2022-03-17 修订日期：2022-07-29 |
| DOI： |
| 中文关键词: 老年 2型糖尿病 认知功能 衰弱 影响因素 |
| 英文关键词:old age type 2 diabetes mellitus cognitive function decline influencing factors. |
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| 中文摘要: |
| 摘要：目的 调查老年2型糖尿病（type 2 diabetes mellitus，T2DM）患者认知衰弱状况及影响因素，为老年T2DM认知衰弱的防治提供依据。方法 于2021年1月-2021年12月选取浙江大学医院院附属杭州市第一人民医院内分泌科收治的老年（≥60岁）T2DM患者为研究对象。收集患者一般资料，采用精神状态评估量表（MMSE）、衰弱身体表型量表（Fried）、简易营养评估量表（MNA-SF）测量患者认知功能障碍、躯体衰弱、营养状况，采用多因素Logistic回归模型分析老年T2DM患者认知衰弱的影响因素。结果 223例老年T2DM患者中48例(21.52%)存在认知衰弱。单因素分析显示，不同年龄、文化程度、居住方式、婚姻状况、家庭人均收入、夜间睡眠时长、合并慢病数量、营养状况、抑郁状况、运动习惯的老年T2DM患者认知衰弱发生率比较，差异有统计学意义（均P＜0.05）。多因素Logistic 回归结果显示：年龄(70~79岁：OR=1.850;≥80岁：OR=3.273）、营养不良（OR=4.581）、夜间睡眠时长＜6h（OR=2.609）、 合并慢性病＞2种（OR=2.310）、抑郁（OR=2.956）是老年T2DM患者认知衰弱的危险因素。规律运动（OR=0.304）是老年T2DM患者认知衰弱的保护因素。结论 老年T2DM患者认知衰弱发生率较高，医务人员应加强高龄、营养不良、睡眠质量差、多共病、伴有抑郁及缺乏运动的老年T2DM患者认知衰弱筛查和干预。 |
| 英文摘要: |
| Abstract: Objective To investigate the cognitive decline status of type 2 diabetes mellitus (T2DM) in elderly patients and to explore its influencing factors, so as to provide reference for preventing and treating senile T2DM cognitive decline. Methods: 2 patients with senile cognitive impairment were studied. Methods from January 2021 to December 2021, elderly patients (≥ 60 years old) with T2DM were selected from the Department of endocrinology of Hangzhou first people's Hospital Affiliated to Zhejiang University Hospital. The general data of patients were collected. The cognitive impairment, physical weakness and nutritional status of patients were measured by mental state assessment scale (MMSE), weakened body phenotype scale (fried) and simple nutrition assessment scale (MNA-SF). The influencing factors of cognitive weakness in elderly T2DM patients were analyzed by multivariate logistic regression model. Results a total of 48 (21.52%) elderly patients with T2DM had cognitive weakness. Univariate analysis showed that age, educational level, living style, marital status, per capita family income, night sleep duration, chronic types, nutritional status, depression and persistent exercise were associated with cognitive weakness in elderly patients with T2DM (all P < 0.05). The results of multivariate logistic regression showed that age (70 ~ 79 years old: or = 1.850; ≥ 80 years old: or = 3.273), malnutrition (or = 4.581), Sleep duration at night＜6h (or = 2.609)，More than 2 kinds of chronic diseases (or = 2.310)，depression (or = 2.956), exercise (or = 0.304) .Conclusion The incidence of cognitive impairment in elderly T2DM patients is high. Medical staff should strengthen the screening and intervention of cognitive impairment in elderly T2DM patients with old age, malnutrition, poor sleep quality, multiple comorbidities, depression and lack of exercise. |
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