| 吴延延,王苏,乔建军,方红.以皮疹为首发的血管免疫母细胞性T细胞淋巴瘤1例[J].浙江中西医结合杂志,2022,32(12): |
| 以皮疹为首发的血管免疫母细胞性T细胞淋巴瘤1例 |
| A case of angioimmunoblastic T cell lymphoma with skin damage as the initial symptom |
| 投稿时间：2022-03-17 修订日期：2022-07-26 |
| DOI： |
| 中文关键词: 皮肤 T细胞淋巴瘤 血管免疫母细胞性T细胞淋巴瘤 |
| 英文关键词:Skin T-cell lymphoma Angioimmunoblastic T-cell lymphoma |
| 基金项目: |
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| 中文摘要: |
| 患者,女,50岁,因躯干泛发丘疹、结节、斑块伴有剧烈瘙痒一年,肢体肿胀半年就诊。多次抗炎、抗过敏治疗无效。皮肤组织病理示：表皮大致正常,真皮浅层及皮肤附件周围中等大小异性T淋巴样细胞浸润。皮损免疫组化示：CD3、CD4、CD8、TIA1均(+),CD30部分(+),Ki67 (50%+)(图3),ALK、CD20、CD56、EMA、GB均(-)。病理诊断：考虑为外周T细胞性非霍奇金淋巴瘤早期改变。诊断：血管母细胞性T细胞淋巴瘤。诊断：血管母细胞性T细胞淋巴瘤。行CHOP方案化疗,皮肤症状好转。 |
| 英文摘要: |
| A 50-year-old female presented with widespread papules, nodules, and plaques on the trunk accompanied by intense itching for one year and swelling of the limbs for half year. She has been ineffective after repeated anti-inflammatory and anti-allergic treatments. Histopathology of the skin showed that the epidermis was roughly normal, and the superficial dermis and around the skin appendages were infiltrated with heterogeneous T lymphoid cells of medium size. The skin lesion immunohistochemistry showed: CD3, CD4, CD8, TIA1 all (+), CD30 part (+), Ki67 (50%+) (Figure 3), ALK, CD20, CD56, EMA, GB all (-); pathological diagnosis: consider the early changes of peripheral T-cell non-Hodgkin"s lymphoma. Diagnosis: Hemangioblastic T-cell lymphoma. Diagnosis: Hemangioblastic T-cell lymphoma. After CHOP chemotherapy, the patient skin symptoms improved. |
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