| 陈雅庆,李伟,茹融融.乳腺浸润性小叶癌超声特征与腋窝淋巴结转移的相关性研究[J].浙江中西医结合杂志,2023,33(7): |
| 乳腺浸润性小叶癌超声特征与腋窝淋巴结转移的相关性研究 |
| CORRELATION BETWEEN ULTRASONIC FEATURES OF INVASIVE LOBULAR CARCINOMA OF THE BREAST AND AXILLARY LYMPH NODE METASTASIS |
| 投稿时间：2022-05-10 修订日期：2023-06-25 |
| DOI： |
| 中文关键词: 浸润性小叶癌 超声 腋窝淋巴结 CA153 分子分型 |
| 英文关键词:Invasive lobular carcinoma Ultrasound Axillary lymph node CA153 Molecular classification |
| 基金项目:浙江省卫生健康科技计划（2022KY1058） |
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| 中文摘要: |
| [目的]本研究旨在探讨乳腺浸润性小叶癌(Invasive lobular carcinoma,ILC)患者腋窝淋巴结转移(axillary lymph node metastasis, ALNM)的超声特征及其他参数影响因素。[方法]收集病理已证实为ILC且术前行超声检查的病例91例,根据有无腋窝淋巴结转移分为ALNM组和无ALNM组,采用回顾性研究,收集患者的超声图像特征、术前CA153以及免疫指标等。[结果] 91例ILC患者中,45例发生ALNM,46例未发生ALNM。单因素x2分析显示,病灶>23.5mm、纵横比≧1、周边高回声晕等超声特征,以及术前CA153>6.5U/ml与ALNM有关(P<0.05)。多因素logistic回归分析显示,周边高回声晕和术前CA153>6.5U/ml是影响ILC患者ALNM的独立危险因素(P<0.05)。[结论]周边高回声晕和术前CA153>6.5U/ml是影响ILC患者发生ALNM的独立危险因素,可作为临床实践参考指标。 |
| 英文摘要: |
| [Objective] The aim of this study was to explore the factors that affect axillary lymph node metastasis (ALNM)in invasive lobular carcinoma (ILC) patients in the terms of ultrasonic characteristics and other parameters. [Methods] Ninety-one patients who diagnosed with ILC pathologically and had preoperative ultrasonography were divided into ALNM group and non-ALNM group according to whether axillary lymph node metastasis was present. Ultrasound image characteristics, preoperative CA153 and immune indicators of patients were collected in a retrospective study. [Results] Among 91 patients with ILC, 45 patients had ALNM, and 46 patients had no ALNM. Univariate x2 analysis showed that ALNM was associated with ultrasound features such as lesions >23.5mm, aspect ratio≧1, peripheral hyperechoic halo, and preoperative CA153>6.5U/ mL (P<0.05). Multivariate logistic regression analysis showed that peripheral hyperechoic halo and preoperative CA153>6.5U/mL were independent risk factors for ALNM in ILC patients (P<0.05). [Conclusion] Peripheral hyperechoic halo and preoperative CA153>6.5U/ mL are independent risk factors for ALNM in ILC patients, which can be used as a reference index in clinical practice. |
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