| 管月帆,陈坚翱,高灵俊,何俊玲.乳腺癌患者的流行病学特点及中医证型分布的临床研究[J].浙江中西医结合杂志,2022,32(9): |
| 乳腺癌患者的流行病学特点及中医证型分布的临床研究 |
| Clinical study on epidemiological characteristics and TCM syndrome type distribution of breast cancer patients |
| 投稿时间:2022-05-10 修订日期:2022-05-31 |
| DOI: |
| 中文关键词: 乳腺癌 流行病学 中医证型 分布特征 治未病 |
| 英文关键词:Breast cancer Epidemiology TCM syndrome type Distribution characteristics Cure not ill |
| 基金项目:浙江省中医药科技计划项目(NO.2021ZA092) |
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| 中文摘要: |
| 目的:从流行病学特点及中医辨证分型分布探索预防和治疗乳腺癌的新思路。方法:通过回顾性调查分析,收集457例乳腺癌住院患者的流行病学基本信息、病理类型和中医辨证分型等情况,分析乳腺癌患者流行病学特点,以及病理类型与中医证型相关性。结果:纳入病例均为女性,≥45周岁的患者358例(78.34%);产次>1次的患者274例(59.96%),引流产次>1次的患者324例(70.90%);有吸烟史的患者30例(6.56%),有饮酒史的患者19例(4.16%);无家族肿瘤疾病史的患者415例(90.81%)。病理类型中浸润性癌(303例)占比最大,中医证型中肝郁痰凝证(246例)、冲任失调证(128例)例数较多。病理类型与中医证型相关性结果显示早期浸润癌与肝郁痰凝证呈正相关(P<0.05),浸润性癌与肝郁痰凝证、冲任失调证呈正相关(P<0.05)。结论:乳腺癌患者中医证型多为肝郁痰凝证、冲任失调证,早期浸润癌与肝郁痰凝证,浸润性癌与肝郁痰凝证、冲任失调证具有明显相关性,该结果为中医“治未病”理论预防和治疗乳腺癌提供了新思路与新方法。 |
| 英文摘要: |
| Objective: To explore a new way of preventing and treating breast cancer from the epidemiological characteristics and TCM syndrome differentiation and distribution.Methods: Through retrospective epidemiological investigation and analysis, the basic epidemiological information, pathological types and TCM syndrome differentiation and distribution of 457 breast cancer patients were collected, and the epidemiological characteristics of breast cancer patients were analyzed, as well as the correlation between pathological types and TCM syndrome types.Results: All included cases were female, 358 patients(78.34%) ≥45 years old. 324 patients (70.90%) with >1 pregnancy, 274 cases (59.96%) were induced abortion times >1; There were 30 patients with smoking history (6.56%) and 19 patients with drinking history (4.16%). There were 415 patients (90.91%) without family history of tumor disease. Among the pathological types, invasive cancer (303 cases) accounted for the largest proportion, and among TCM syndromes, liver stagnation and phlegm coagulation syndrome (246 cases) and maladjustment of Chong-ren syndrome (128 cases) were more cases. The results of correlation between pathological types and TCM syndromes showed that early invasive cancer was positively correlated with liver stagnation and spittoon coagulation syndrome (P<0.000), while invasive cancer was positively correlated with liver stagnation and spittoon coagulation syndrome and maladjustment of Chong-ren syndrome (P<0.000).Conclusion: The traditional Chinese medicine syndromes of breast cancer patients are mainly liver stagnation and phlegm coagulation syndrome and maladjustment of Chong-ren syndrome, early infiltrating cancer and liver stagnation and phlegm coagulation syndrome, infiltrating cancer has obvious correlation with liver stagnation and phlegm coagulation syndrome and maladjustment of Chong-ren syndrome, this result provides a new idea for the treatment and prevention of breast cancer. |
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