| 黄创豪,过建春,荀运浩.基于中医传承辅助平台探讨过建春教授治疗慢加急性肝衰竭的用药经验[J].浙江中西医结合杂志,2023,33(8): |
| 基于中医传承辅助平台探讨过建春教授治疗慢加急性肝衰竭的用药经验 |
| Analysis of Guo Jianchun’s Medication Experience in Treating Acute-On-Chronic Liver Failure based on Traditional Chinese Medicine Inheritance Support System |
| 投稿时间：2023-02-24 修订日期：2023-06-02 |
| DOI： |
| 中文关键词: 过建春 慢加急性肝衰竭 中医传承辅助平台 用药规律 数据挖掘 |
| 英文关键词:Guo Jianchun Acute-On-Chronic Liver Failure Traditional Chinese Medicine Inheritance Support System medication rules |
| 基金项目:浙江省中医药科技计划项目(No.2021ZB234)；浙江省名老中医专家传承工作室建设项目(No.GZS2020035) |
|
| 摘要点击次数: 562 |
| 全文下载次数: 2 |
| 中文摘要: |
| 目的 基于中医传承辅助平台（TCMISS V2.5）挖掘分析过建春教授治疗慢加急性肝衰竭的中医用药经验。方法 选择杭州市西溪医院2019年1月至2022年6月过建春教授治疗慢加急性肝衰竭的病例，筛选处方，建立数据库，利用中医传承辅助平台的频次统计、关联规则Apriori算法、复杂系统熵聚类等统计方法，对数据进行分析，根据分析结果探讨过师治疗ACLF的用药经验。结果 共筛选出处方70首，涉及常用药物112味，药性以寒、平为多，药味以甘、苦为主，归脾、胃、肝经药物最常见，茵陈、扯根菜、甘草、鸡内金、赤芍、半枝莲、丹参、蒲公英为核心药物，演化得到3首新处方。结论 过建春教授治疗慢加急性肝衰竭以凉血解毒利湿为先，以健运脾胃为要，随症加减，标本兼治，体现了过建春教授治疗慢加急性肝衰竭灵活辨治的思想，为中医药治疗慢加急性肝衰竭提供了参考价值。 |
| 英文摘要: |
| Abstract Objective: To explore the medication experience of Professor Guo Jianchun in the treatment of Acute-On-Chronic Liver Failure(ACLF) with the use of Traditional Chinese Medicine Inheritance Support System(TMISS V2.5). Methods: Collect and screene cases of ACLF which Professor Guo Jianchun used to treating in Hangzhou Xixi Hospital from January 2019 to June 2022. Enter the data into TMISS and build a private database. Analyze the data by frequency statistics, association rules and complex system entropy clustering and other statistical methods of TMISS, and discuss the medication experience of Professor Guo Jianchun according to the analysis results. Results: A total of 70 prescriptions for ACLF were selected, involving 112 Chinese drugs. The medicinal properties were mainly cold and flat, the taste was mainly sweet and bitter, and the meridian was mainly spleen, stomach and liver. The most frequently used drugs were Yinchen, Chegencai, Gancao, Jineijin, Chishao, Banzhilian, Danshen, Pugongying. Three new prescriptions for treating ACLF were obtained through the new square analysis. Conclusion: Professor Guo Jianchun treated ACLF mainly by heat-clearing, detoxifying and dampness-removing, as well as invigorating spleen and stomach. Increasing or decreasing the medication as the symptoms change, to treat both the symptoms and root causesboth the symptoms and root causes, reflecting Professor Guo Jianchun’s flexible thinking in treating ACLF, which provides reference value for treating ACLF with traditional Chinese medicine. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
