| 龚远青.针刀刺营疗法对鼻源性慢性咽炎疗效及对炎症因子、T淋巴细胞亚群、SIgA水平的影响[J].浙江中西医结合杂志,2024,34(10): |
| 针刀刺营疗法对鼻源性慢性咽炎疗效及对炎症因子、T淋巴细胞亚群、SIgA水平的影响 |
| Efficacy of acupuncture camp therapy on rhinogenic chronic pharyngitis and its effect on inflammatory factors, T lymphocyte subsets, and SIgA levels |
| 投稿时间：2023-08-04 修订日期：2024-09-06 |
| DOI： |
| 中文关键词: 针刀刺营疗法 鼻源性慢性咽炎 炎症因子 T淋巴细胞亚群 SigA |
| 英文关键词:Acupuncture camp therapy Chronic pharyngitis of nasal origin Inflammatory factors T cell subset SIgA |
| 基金项目:嘉兴市科技计划项目；编号：2020AD30023 |
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| 中文摘要: |
| 目的 探讨针刀刺营疗法对鼻源性慢性咽炎疗效及对炎症因子、T淋巴细胞亚群、SIgA水平的影响。方法 回顾性选取2021年1月-2023年1月我院100例鼻源性慢性咽炎患者随机数字表法分为试验组(50例)和对照组(50例),试验组采用盱江谢氏针刀刺营疗法治疗,对照组采用西药(庆大霉素等雾化)治疗。两组治疗周期都为2个疗程共14天(7天/疗程)。比较两组患者治疗前后中医症候积分；对患体治疗前后体内血清炎症因子、T淋巴细胞亚群(T cell subset)、分泌型免疫球蛋白A(Secretory Immunoglobulin A ,SIgA)水平进行检测。治疗后两周、三个月时对两组患者进行随访和复诊,收集比较两组患者疗效总有效率、生活质量综合评定量表(GQOLI-74)。结果 治疗2疗程后对患者随访和复诊发现两周时两组总有疗效相差不大,第3个月时试验组总有效率要显著高于对照组,差异具有统计学意义(P<0.05)；试验组生活质量综合评定量表(GQOLI-74)评分显著高于对照组且治疗后中医症候积分试验组低于对照组,差异具有统计学意义(P<0.05);治疗后两组患者炎症因子水平均降低,且试验组要低于对照组,差异具有统计学意义(P<0.05);试验组和对照组治疗后T细胞亚群(CD3+、CD4+、CD4+/CD8+)和SigA水平提高,且经治疗后试验组各项指标水平提高显著优于对照组,差异具有统计学意义(P<0.05)。结论 谢氏针刀刺营疗法治疗鼻源性慢性咽炎疗效确切,能有效缓解患者症状体征,显著改善患者生活质量,降低患者体内炎症反应并调节体内T淋巴亚群、SigA水平,同时兼具安全、简便 、价廉 、无药物副作用、对患者创伤小等优点的自然疗法。 |
| 英文摘要: |
| Objective To investigate the efficacy of acupuncture camp therapy on nasal chronic pharyngitis and its effects on inflammatory factors, T lymphocyte subsets and SIgA levels. Methods A retrospective selection of 100 patients with nasal chronic pharyngitis in our hospital from January 2021-January 2023 was divided into experimental group (50 cases) and control group (50 cases), the experimental group was treated by Xie"s acupuncture camp therapy, and the control group was treated with western medicine (gentamicin and other atomization). Both groups had 2 courses of treatment for a total of 14 days (7 days/course). The scores of TCM symptoms before and after treatment of the two groups were compared. The levels of serum inflammatory factors, T cell subsets, and secretory immunoglobulin A (SigA) in? body before and after treatment were measured. Two weeks and three months after treatment, the two groups of patients were followed up and followed, and the comprehensive rating scale (GQOLI-74) of total response rate and quality of life of the two groups was collected and compared. Results After the second course of treatment, the follow-up and follow-up of the patients showed that the total efficacy of the two groups was not much different at two weeks, and the total effective rate of the experimental group was significantly higher than control group at third month, and the difference was statistically significant (P<0.05). The score of the comprehensive quality of life rating scale (GQOLI-74) in experimental group was significantly higher than control group, and the score of TCM symptoms after treatment was lower than control group, and difference was statistically significant (P<0.05). After treatment,? Levels of inflammatory factors in both groups were reduced, and the experimental group was lower than that in the control group, and? difference was statistically significant (P<0.05). The levels of T cell subsets (CD3+, CD4+, CD4+/CD8+) and SigA increased between the experimental group and the control group after treatment, and the levels of various indexes in the experimental group after treatment were significantly better than those in the control group, and difference was statistically significant (P<0.05). Conclusion Xie"s acupuncture camp therapy has a definite effect in the treatment of nasal chronic pharyngitis, can effectively relieve the symptoms and signs of patients, significantly improve the quality of life of patients, reduce the inflammatory response in patients, regulate the level of T lymphoid subsets and SigA in the body, and at the same time have the advantages of safety, simplicity, low price, no drug side effects, and less trauma to patients. |
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