| 来文华,丁力,江晓煜,黄梦瑜,余燕燕,胡佳蝶,孙丹,邬成霖,高宜云.杭州市萧山区0.5~12岁儿童特应性皮炎流行病学调查[J].浙江中西医结合杂志,2024,34(6): |
| 杭州市萧山区0.5~12岁儿童特应性皮炎流行病学调查 |
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| 投稿时间：2023-12-25 修订日期：2024-03-19 |
| DOI： |
| 中文关键词: 特应性皮炎 流行病学 患病率 |
| 英文关键词: |
| 基金项目: |
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| 中文摘要: |
| 目的：了解杭州市萧山区0.5~12岁儿童特应性皮炎（AD）最新的患病情况。
方法：2022年4月至2022年8月选择杭州市萧山区北干街道作为调查点，以0.5~12岁儿童为调查对象，通过整群抽样的方法确定具体对象，以预防接种门诊、儿保门诊以及幼儿园、小学为调查现场。采用问卷与体检相结合的方式，进行特应性皮炎及相关因素的流行病学调查。
结果：共回收有效调查问卷14313份，年龄0.5~12岁。符合AD诊断标准者共1259例，其中男676例，女583例。总的患病率为8.80%，男性患病率为9.18%，女性患病率为8.39%。患病率经过标化后，总标化患病率为8.794%，男性标化患病率为9.039%，女性标化患病率为8.392%，两者间标化患病率差异没有显著性（P>0.05）。随年龄增长，AD的总体患病率逐步降低，同时患儿数量随发病年龄的增长而显著减少。年龄与合并过敏性鼻炎、哮喘、曲侧皮肤受累史、花粉过敏、尘螨过敏、一级亲属有特应性疾病史等因素有显著相关性（P<0.05）。发病年龄与合并过敏性鼻炎、哮喘、食物或药物过敏史、一级亲属有特应性疾病史的比例有显著相关性（P<0.05）。
结论：2022年4-8月所调查的杭州市萧山区0.5~12岁儿童AD的标化患病率为8.794%，相较以往的AD流行病学调查数据呈现上升趋势，且AD患病率与年龄呈显著的负相关。 |
| 英文摘要: |
| Objective: To understand the latest prevalence of atopic dermatitis (AD) in children aged 0.5 to 12 years in Xiaoshan District of Hangzhou.
Method: From April 2022 to August 2022, the Beigan Street of Xiaoshan District, Hangzhou City was selected as the survey site. Children aged 0.5 to 12 years were selected as the survey subjects. The specific subjects were determined through cluster sampling, and the investigation was conducted at vaccination clinics, pediatric clinics, kindergartens, and primary schools. A combination of questionnaire and physical examination was used to conduct an epidemiological investigation of atopic dermatitis and related factors.
Results: A total of 14,313 valid questionnaires were collected from individuals aged 0.5 to 12 years. Among them, 1,259 cases met the diagnostic criteria for atopic dermatitis (AD), with 676 males and 583 females. The overall prevalence rate was 8.80%, with a male prevalence rate of 9.18% and a female prevalence rate of 8.39%. After standardization, the overall standardized prevalence rate was 8.794%, with the male standardized prevalence rate at 9.039% and the female standardized prevalence rate at 8.392%. There was no significant difference in the standardized prevalence rates between the genders (P<0.05). The prevalence of AD gradually decreased with increasing age. Additionally, age was significantly associated with concomitant allergic rhinitis, asthma, history of eczema, pollen allergy, dust mite allergy, and a family history of atopic diseases (P<0.05). There was no significant association between AD and a history of food or drug allergies or a history of generalized skin dryness (P>0.05).
Conclusion: The standardized prevalence rate of AD in children aged 0.5 to 12 years in Xiaoshan District of Hangzhou from April to August 2022 was 8.794%. Compared to previous epidemiological survey data on AD, the prevalence of AD is showing an increasing trend, and the prevalence of AD is significantly negatively correlated with age. |
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