| 胡逸军.自拟涤痰汤辅助常规西药治疗冠心病稳定型心绞痛痰浊内阻证临床研究[J].浙江中西医结合杂志,2025,35(1): |
| 自拟涤痰汤辅助常规西药治疗冠心病稳定型心绞痛痰浊内阻证临床研究 |
| A Clinical Study on Self formulated Ditan Tang Assisting Conventional Western Medicine in the Treatment of Stable Angina Pectoris of Coronary Heart Disease with Phlegm Turbidity and Internal Obstruction Syndrome |
| 投稿时间：2024-03-06 修订日期：2024-11-27 |
| DOI： |
| 中文关键词: 冠心病 稳定型心绞痛 痰浊内阻证 自拟涤痰汤 血脂 |
| 英文关键词:Coronary heart disease Stable angina pectoris Phlegm turbidity and internal obstruction syndrome Self-made Ditan Tang Clinical efficacy |
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| 中文摘要: |
| 目的:研究观察对冠心病稳定型心绞痛痰浊内阻证患者采用自拟涤痰汤辅助常规西药治疗的临床效果。方法:以随机数字表法将兰溪市中医院收治的102例冠心病稳定型心绞痛痰浊内阻证患者分为2组,各51例,对照组给予常规西医治疗,治疗组给予自拟涤痰汤辅助常规西药治疗,均连续治疗2个月后比较临床疗效,评估心绞痛症状(发作次数、疼痛程度、平均发作时间)、硝酸甘油用量及中医证候积分,检测血脂[三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)]水平变化。结果:治疗组总有效率高于对照组(96.08% vs 84.31%)(P＜0.05)。治疗后,2组心绞痛发作次数低于治疗前,疼痛程较治疗前减轻,平均发作时间短于治疗前,硝酸甘油用量少于治疗前(P＜0.05),治疗组各方面改善情况优于对照组(P＜0.05)；治疗后,2组中医证候积分较治疗前明显降低(P＜0.05),治疗组低于对照组(P＜0.05)；治疗后,2组TC、TG水平较治疗前明显降低(P＜0.05),治疗组低于对照组(P＜0.05)；2组治疗前后HDL-C、LDL-C相比均无统计学差异(P＞0.05)。结论:针对冠心病稳定型心绞痛痰浊内阻证患者以自拟涤痰汤辅助治疗效果显著,对减轻症状体征、缓解疼痛程度、降低心绞痛发作次数、缩短发作时间及减少硝酸甘油用量有积极作用,且有效降低患者三酰甘油、总胆固醇含量。 |
| 英文摘要: |
| Objective: To study and observe the clinical effect of using self-made Ditan Tang as an adjunct to conventional Western medicine treatment on patients with stable angina pectoris and phlegm obstruction syndrome in coronary heart disease. Methods: Method: 102 patients with stable angina pectoris of coronary heart disease and phlegm obstruction syndrome admitted to Lanxi Traditional Chinese Medicine Hospital were divided into two groups using a random number table method, with 51 cases in each group. The control group received conventional Western medicine treatment, while the treatment group received self formulated Ditan Tang supplemented with conventional Western medicine treatment. After two consecutive months of treatment, the clinical efficacy was compared, and the symptoms of angina pectoris (number of attacks, degree of pain, average attack time), nitroglycerin dosage, and traditional Chinese medicine syndrome score were evaluated, Detect changes in blood lipid levels such as triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C), and low-density lipoprotein (LDL-C). Result: The total effective rate of the treatment group was higher than that of the control group (96.08% vs 84.31%) (P<0.05). After treatment, the number of angina attacks in both groups was lower than before treatment, the pain duration was reduced, the average attack time was shorter than before treatment, and the amount of nitroglycerin used was less than before treatment (P<0.05). The improvement in all aspects of the treatment group was better than that of the control group (P<0.05); After treatment, the TCM syndrome scores of the two groups significantly decreased compared to before treatment (P<0.05), and the treatment group was lower than the control group (P<0.05); After treatment, the levels of TC and TG in both groups were significantly reduced compared to before treatment (P<0.05), and the treatment group was lower than the control group (P<0.05); There was no statistically significant difference in HDL-C and LDL-C between the two groups before and after treatment (P>0.05). Conclusion: For patients with stable angina pectoris of coronary heart disease with phlegm turbidity and internal obstruction syndrome, the use of self-made Ditan Tang as an adjuvant treatment has a significant effect. It has a positive effect on reducing symptoms and signs, alleviating pain, reducing the frequency of angina attacks, shortening attack time, and reducing nitroglycerin dosage, and effectively reducing the content of triacylglycerol and total cholesterol in patients. |
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