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江萍,何小君.GLIM应用于NRS2002≥3分恶性肿瘤患者营养不良诊断中的价值[J].浙江中西医结合杂志,2025,35(3):
GLIM应用于NRS2002≥3分恶性肿瘤患者营养不良诊断中的价值
Value of GLIM in the diagnosis of malnutrition in patients with NRS2002 score ≥3
投稿时间:2024-04-03  修订日期:2025-01-26
DOI:
中文关键词:  全球领导人营养不良倡议  患者主观整体评估  营养不良  营养风险筛查2002  恶性肿瘤
英文关键词:Global Leaders Malnutrition Initiative  Patient subjective global assessment  Malnutrition  Nutritional Risk Screening 2002  Malignant tumor
基金项目:
作者单位E-mail
江萍 舟山医院 JP15858093907@163.com 
何小君* 舟山医院 HXJ15957092520@163.com 
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中文摘要:
      目的:研究全球领导人营养不良倡议(GLIM)应用于营养风险筛查2002(NRS2002)≥3分恶性肿瘤患者营养不良诊断中的价值并予以分析。方法:选取医院从2023年6月到2023年12月收治的80例恶性肿瘤患者作为研究对象。分别选用GLIM标准即患者主观整体评估(PG-SGA)标准评估患者营养不良发生情况,比较分析上述两种方法诊断恶性肿瘤患者营养不良的一致性。此外,选用多因素Logistic回归分析明确GLIM标准下NRS2002≥3分恶性肿瘤患者营养不良的危险因素。结果:按照GLIM标准,80例恶性肿瘤患者营养不良人数56例,发生率为70.00%;年龄≥70岁、消化系统肿瘤及TNM分期Ⅲ-Ⅳ期患者营养不良发生率均高于年龄<70岁、其他系统肿瘤及TNM分期Ⅰ-Ⅱ期患者(均P<0.05)。按照PG-SGA标准,80例恶性肿瘤患者营养不良人数58例,发生率为72.50%;男性、年龄≥70岁、消化系统肿瘤及TNM分期Ⅲ-Ⅳ期患者营养不良发生率均高于女性、年龄<70岁、其他系统肿瘤及TNM分期Ⅰ-Ⅱ期患者(均P<0.05)。将PG-SGA诊断结果视作金标准,GLIM诊断营养不良的灵敏度、特异度、准确性为94.83%(55/58)、95.45%(21/22)、95.00%(76/80),Kappa值为0.878。经多因素Logistic回归分析证实,NRS2002≥3分恶性肿瘤患者营养不良的危险因素共4项:①男性;②年龄≥70岁;③消化系统肿瘤;④TNM分期Ⅲ-Ⅳ期(均P<0.05)。结论:GLIM与PG-SGA在NRS2002≥3分恶性肿瘤患者营养不良的诊断中存在良好一致性。
英文摘要:
      Objective: To investigate and analyze the value of the Global Leaders Malnutrition Initiative (GLIM) in the diagnosis of malnutrition in malignant tumor patients with nutritional Risk Screening 2002 (NRS2002) score ≥3. Methods: A total of 80 patients with malignant tumor admitted from June 2023 to June 2024 were selected as subjects. GLIM criteria, i.e., PG-SGA criteria, were used to evaluate the incidence of malnutrition in patients, and the consistency of the above two methods in the diagnosis of malnutrition in patients with malignant tumors was compared and analyzed. In addition, multivariate Logistic regression analysis was used to determine the risk factors of malnutrition in malignant tumor patients with NRS2002 score ≥3 under GLIM criteria. Results: According to GLIM criteria, 56 of 80 patients with malignant tumor were malnourished, with an incidence of 70.00%. The incidence of malnutrition in patients aged ≥70 years, digestive system tumor and TNM stage Ⅲ-Ⅳ was higher than that in patients aged < 70 years, other system tumor and TNM stage Ⅰ-Ⅱ (all P< 0.05). According to the PG-SGA standard, 58 of the 80 patients with malignant tumors were malnourished, with an incidence of 72.50%. The incidence of malnutrition in male, age ≥70 years old, digestive system tumor and TNM stage Ⅲ-Ⅳ patients was higher than that in female, age < 70 years old, other system tumor and TNM stage Ⅰ-Ⅱ patients (all P< 0.05). The diagnostic results of PG-SGA were regarded as the gold standard. The sensitivity, specificity and accuracy of GLIM in the diagnosis of malnutrition were 94.83% (55/58), 95.45% (21/22), 95.00% (76/80), and Kappa value was 0.878. Multivariate Logistic regression analysis confirmed that there were four risk factors for malnutrition in malignant tumor patients with NRS2002 score ≥3: ① male; ② Age ≥70 years old; ③ digestive system tumor; ④TNM stage Ⅲ-Ⅳ (all P < 0.05). Conclusion: GLIM and PG-SGA are consistent in the diagnosis of malnutrition in malignant tumor patients with NRS2002 score ≥3.
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