| 周小凯,金奇志,傅安艺,管敏敏.神香苏合丸联合西医治疗急性心肌梗死PCI术后微血管心绞痛患者临床观察[J].浙江中西医结合杂志,2024,34(10): |
| 神香苏合丸联合西医治疗急性心肌梗死PCI术后微血管心绞痛患者临床观察 |
| Clinical observation of Shenxiangsuhe pill combined with western medicine in the treatment of patients with microvascular angina pectoris after PCI of acute myocardial infarction |
| 投稿时间：2024-04-19 修订日期：2024-05-24 |
| DOI： |
| 中文关键词: 神香苏合丸 西医治疗 急性心肌梗死 冠状动脉支架植入术后 微血管心绞痛 血管内皮 心功能 |
| 英文关键词:Shenxiangsuhe pill Western medicine treatment Acute myocardial infarction After coronary artery stenting Microvascular angina Vascular endothelium Cardiac function |
| 基金项目:浙江省医学会临床科研(2022ZYC-A113) |
|
| 摘要点击次数: 339 |
| 全文下载次数: 1 |
| 中文摘要: |
| 目的:探讨神香苏合丸联合西医治疗急性心肌梗死PCI术后微血管心绞痛患者临床疗效。方法：选择于我院就诊的急性心肌梗死PCI术后微血管心绞痛患者118例,采用随机对照研究分为观察组与对照组各59例,对照组患者给予西药治疗,对照组在其基础上给予神香苏合丸治疗。观察两组患者中医证候评分,血管内皮功能[血管内皮功能指数(RHI)、血管紧张素Ⅱ(AngⅡ)、内皮素-1(ET-1)],心功能情况[血清N末端脑钠肽前体(NT-proBNP)、左心室射血分数(LVEF)、每搏输出量(SV)]、西雅图心绞痛量表(SAQ)评分及临床疗效。结果：治疗后观察组总有效率93.22%显著高于对照组83.05%(P＜0.05)。治疗后2组中医证候评分、ET-1、AngⅡ、NT-proBNP水平均较治疗前降低,RHI指数、LVEF值、SV值、SAQ评分均治疗前升高,且观察组降低/升高幅度大于对照组(P＜0.05)。结论：神香苏合丸联合西医治疗急性心肌梗死PCI术后微血管心绞痛患者临床疗效显著。 |
| 英文摘要: |
| Objective: To explore the clinical effect of Shenxiangsuhe pill combined with western medicine in the treatment of patients with microvascular angina pectoris after PCI of acute myocardial infarction. Methods: 118 patients with microvascular angina pectoris after PCI were selected from our hospital, 59 cases in each group by a prospective randomized controlled study. The control group was given medicine of traditional, and the observe group was given shenxiangsuhe pill in the basis of western medicine treatment. The clinical efficacy, TCM syndrome score, vascular endothelial function [Vascular endothelial function index (RHI), angiotensin Ⅱ(AngⅡ), endothelin-1 (ET-1)] of the two groups were observed before and after treatment. Cardiac function [serum N-terminal brain natriuretic peptide precursor (NT-proBNP), left ventricular ejection fraction (LVEF), stroke output (SV)] and Seattle Angina Scale (SAQ) score. Results: After treatment, the observation group total effective rate of 93.22% higher than 83.05% in control group (P < 0.05). After treatment, the TCM syndrome score, ET-1, AngⅡ and NT-proBNP levels of the 2 groups were all decreased compared with before treatment, and the RHI index, LVEF value, SV value and SAQ score were all increased before treatment, (P < 0.05). Conclusion: Shenxiangsuhe pill combined with western medicine is effective in the treatment of patients with microvascular angina pectoris after PCI of acute myocardial infarction. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
