| 黄银,谢小红,许雷来.热敏灸联合阳和汤加减治疗非哺乳期乳腺炎肿块期的临床疗效观察[J].浙江中西医结合杂志,2025,35(6): |
| 热敏灸联合阳和汤加减治疗非哺乳期乳腺炎肿块期的临床疗效观察 |
| Clinical effect of heat-sensitive moxibustion combined with Yanghe decoction to treat non-puerperal mastitis |
| 投稿时间：2024-06-29 修订日期：2025-03-08 |
| DOI： |
| 中文关键词: 非哺乳期乳腺炎 热敏灸 临床疗效 炎症因子 |
| 英文关键词:non-puerperal mastitis heat-sensitive moxibustion clinical efficacy inflammatory factors |
| 基金项目:浙江省中医药科技计划(2023ZL416) |
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| 中文摘要: |
| 目的 探讨热敏灸治疗非哺乳期乳腺炎肿块期的临床疗效和作用机制。方法 选取2022年7月至2024年1月在浙江省中医院乳腺科就诊的非哺乳期乳腺炎（肿块期阳虚寒凝证）患者50例，随机分为对照组（n=25）和试验组（n=25），对照组行阳和汤加减治疗，试验组在对照组的基础上在膻中、天池、中脘、膈俞、肝俞、肩贞等穴位探寻热敏腧穴行热敏灸治疗。观察两组患者治疗前后GMDAI指数，疗效指数，临床体征及血清炎症水平变化情况和总有效率。结果 治疗前，两组患者一般资料，治疗前GMDAI指数，临床体征，血清炎症水平差异无统计学意义（P≥0.05）。治疗后两组相比，试验组总有效率、疗效指数更高，在肿块直径、乳房皮肤肤色、肿块硬度、GMDAI指数，WBC、白细胞介素（inter leukin，IL）-6较对照组降低程度更大，差异均有统计学意义（P＜0.05）。两组治疗后的疼痛评分，C反应蛋白均虽有差异，但差异无统计学意义（P≥0.05）。结论 热敏灸治疗非哺乳期乳腺炎肿块期有一定的疗效，可能与控制炎症反应，改善局部症状有关。 |
| 英文摘要: |
| Objective To explore the clinical efficacy and action mechanism of heat-sensitive moxibustion in non-puerperal mastitis. Methods 50 patients with non-puerperal mastitis (mass stage Yang deficiency and cold coagulation) from July 2022 to the Breast Department of Zhejiang Hospital of Traditional Chinese Medicine in January 2024 were randomly divided into the control group (n=25) and the experimental group (n=25), the control group was treated with Yanghe Tang plus and minus and The experimental group was treated with heat-sensitive moxibustion on the Danzhong、Tianchi、Chungwan、Geshu、Ganshu and other acupoints in addition to the treatment in the control group, the changes in GMDAI score, therapeutic index,clinical sign and serum inflammatory level before and after treatment were observed, and the total effective rate was calculated. Results Before treatment, the GMDAI index,clinical sign,and serum inflammation level were not significantly different before treatment (P≥0.05). Compared with the two groups after treatment, the total effective rate and therapeutic index of the experimental group were higher, and the size of the mass,skin color, mass hardness，GMDAI score and WBC、inter leukin (IL-6) were significantly reduced compared with the control group, with statistical significance (P＜0.05).The pain scores、C-reactive protein after treatment were significantly different between the two groups, but the differences were not statistically significant (P≥0.05).Conclusion Heat-sensitive moxibustion has a certain efficacy in the treatment of non-puerperal mastitis, which may be related to the control of inflammatory reaction and improvement of local symptoms. |
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