| 王帅,金志江,施莉萍,童国芳,姜春婷,张益,赵红昌.中医定向透药疗法治疗膝骨关节炎的疗效研究[J].浙江中西医结合杂志,2025,35(1): |
| 中医定向透药疗法治疗膝骨关节炎的疗效研究 |
| Study on the efficacy of Traditional Chinese Medicine directed penetration therapy in the treatment of knee osteoarthritis |
| 投稿时间：2024-07-04 修订日期：2024-10-10 |
| DOI： |
| 中文关键词: 膝关节 骨关节炎 中医定向透药疗法 中西医结合 |
| 英文关键词:Knee Osteoarthritis TCM directed penetration therapy Integration of traditional Chinese and Western medicine |
| 基金项目:浙江省中医药科技计划项目（No.2024ZL763） |
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| Objective: To explore the efficacy of Traditional Chinese Medicine(TCM) directed penetration therapy in the treatment of knee osteoarthritis. Methods: To select KOA patients treated in orthopaedic ward from August 2022 to March 2024, after inclusion criteria and exclusion criteria, 45 patients setted as combination group were applied TCM directed penetration therapy combined with NSAIDs and Cervus and Cucumis polypeptide injection, 48 patients setted as western medicine group were only applied NSAIDs and Cervus and Cucumis polypeptide injection , compare the pain and function scores after 3 days, 7 days and 14 days treatment, the overall treatment efficiency and the incidence of adverse events. Results: There was no significant difference in VAS scores and WOMAC scores between the two groups before treatment. After 3d, 7d and 14d of treatment, the differences of VAS and WOMAC scores between before and after treatment are significant; the VAS score of 7d and 14 days after treatment of combination group was significantly lower than that of western medicine group. There was no significant difference in WOMAC score at 3d and 7d after treatment, and the difference of WOMAC score of 14d after treatment is significant, and the combined group was lower than the western medicine group. The overall efficacy rate in the combination group was higher than that in the western medicine group (86.67% VS 68.75%), the difference was statistically significant. The incidence of adverse events was 13.33% in the combined group and 10.42% in the western medicine group, which was not statistically significant. Conclusion:TCM directed penetration therapy has effective curative effect and clinical application value with low incidence of adverse events for KOA. |
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