| 戚晨云,冯晓霞,陈钦.全国名老中医治疗特发性膜性肾病的用药规律研究[J].浙江中西医结合杂志,2025,35(3): |
| 全国名老中医治疗特发性膜性肾病的用药规律研究 |
| Study on the medication pattern of idiopathic membranous nephropathy treated by the famous veteran doctors in TCM |
| 投稿时间：2024-08-19 修订日期：2025-02-05 |
| DOI： |
| 中文关键词: 特发性膜性肾病 名老中医 用药规律 |
| 英文关键词:diopathic membranous nephropathy, Famous veteran doctors in TCM,Medication rules |
| 基金项目:2023年浙江省中医药科技计划(2023ZL028) |
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| 摘要点击次数: 338 |
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| 中文摘要: |
| 目的:探讨全国名老中医关于特发性膜性肾病治疗的用药规律。方法:收集全国名老中医治疗膜性肾病的符合纳排标准的文献、医案,运用Microsoft Excel构建数据库,通过IBM SPSS Modeler 18.0软件和Lantern5.0软件进行关联规则和隐结构模型分析,对结果分析、归纳和总结,找出用药配伍规律。结果:最终纳入99篇文献,书籍10本,共计医案128例,涉及医家53位。证型多以虚实夹杂为主,本虚多见脾肾亏虚,标实多见血瘀、水湿、湿热等。涉及药物252味,高频药物包括黄芪、茯苓、白术、丹参、当归等,以补虚药、利水渗湿药、活血祛瘀药为主。隐结构模型分析共获得10个隐变量、20个隐类,以方测证推断特发性膜性肾病以脾肾亏虚兼血瘀、水湿为主。结论:特发性膜性肾病患者证型以虚实夹杂为主,名老中医治疗以健脾益肾、利水渗湿、活血化瘀为总体原则。 |
| 英文摘要: |
| Objective: to explore the famous veteran doctors in TCM on the treatment of idiopathic membranous nephropathy(IMN). Methods: We collected the literature and medical cases of national famous veteran doctors in TCM on the treatment of IMN that met the NAMA standards, constructed the database by using Microsoft Excel, and analyzed the association rules and hidden structural model by IBM SPSS Modeler 18.0 software and Lantern5.0 software, analyzed, summarized and summarized the results, and found out the rules of medication. Results: Ninety-nine papers and 10 books were finally included, totaling 128 medical cases involving 53 doctors. Most of the cases were characterized by a mixture of deficiency and excess, with deficiency of the spleen and kidneys as the main deficiency, and blood stasis, water dampness, dampness-heat, etc. as the underlying excess. Involving 252 flavors of herbal medicine, the high-frequency drugs included Astragalus, Poria, Atractylodes macrocephala, Salvia miltiorrhiza, Angelica sinensis, etc., with the main focus on drugs that replenish the deficiency, diuresis and dampness, and activate blood circulation and remove blood stasis. A total of 10 hidden variables and 20 hidden classes were obtained from the hidden structure model analysis, and it was inferred that idiopathic membranous nephropathy was mainly characterized by spleen and kidney deficiency with blood stasis and water-dampness by formula measurement. Conclusions: Patient patterns of IMN were mainly mixed with deficiency and excess, and the treatment of famous veteran doctors in TCM was based on the general principles of tonifying and replenishing the spleen and kidney, eliminating dampness and disinhibiting water, activating blood and resolving stasis. |
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