| 沈妙春.硕通镜钬激光碎石术在复杂性输尿管上段结石中的应用效果[J].浙江中西医结合杂志,2025,35(5): |
| 硕通镜钬激光碎石术在复杂性输尿管上段结石中的应用效果 |
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| 投稿时间：2024-09-12 修订日期：2024-11-22 |
| DOI： |
| 中文关键词: 硕通镜钬激光碎石术 复杂性输尿管上段结石 结石清除率 输尿管镜钬激光碎石术 肾功能 |
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| 摘要点击次数: 218 |
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| 中文摘要: |
| 目的:探究硕通镜钬激光碎石术(STL)在复杂性输尿管上段结石中的应用效果。方法:选取本院泌尿外科住院行手术治疗复杂性输尿管上段结石的患者作为研究对象,共计94例,收治时间为2022年6月~2023年6月。按手术方式的不同分为两组,对照组47例行输尿管镜钬激光碎石术(URHL)治疗,观察组47例行硕通镜钬激光碎石术(STL)治疗。两组患者在全身麻醉下完成手术,比较两组临床疗效、围手术期指标、结石清除率、血清炎性指标[中性粒细胞淋巴细胞比率(NLR)和C反应蛋白(CRP)]及肾功能指标[血肌酐(Scr)、血尿素氮(BUN)]、术后3月并发症及术后1年复发率。结果:术后,与对照组相比,观察组临床疗效总效率较高(P<0.05),手术时间、术中出血量、术后第1天疼痛视觉模拟(VAS)评分及住院时间均较低(P<0.05),术后1周及1月结石清除率较高(P<0.05),术后第1、3天血清NLR、CRP、Scr及BUN水平均较低(P<0.05),术后3月并发症及术后1年复发率均较低(P<0.05)。结论:采用STL治疗复杂性输尿管上段结石能提高临床疗效,提高结石清除率,改善机体炎症和肾功能水平,降低并发症发生率及结石复发率。 |
| 英文摘要: |
| 【 】 Objective:To investigate the effect of holmium laser lithotripsy (STL) in the treatment of complex upper ureteral calculi. Methods: Patients who underwent surgical treatment for complex upper ureteral stones in the Urology Department of our hospital were selected as research subjects, totaling 94 cases, admitted from June 2022 to June 2023. The patients were divided into two groups based on the type of surgery: the control group consisted of 47 patients who underwent ureteroscopic holmium laser lithotripsy (URHL), and the observation group consisted of 47 patients who underwent ShockPulse-SE lithotripsy (STL) treatment. The two groups completed the operation under general anesthesia. The clinical efficacy, perioperative indexes, stone clearance rate, serum inflammatory indexes [neutrophil lymphocyte ratio (NLR) and C-reactive protein (CRP)], renal function indexes [serum creatinine (Scr) and blood urea nitrogen (BUN)], complications 3 months after surgery and recurrence rate 1 year after surgery were compared between the two groups.? Result: After surgery, compared with the control group, the total efficiency of clinical efficacy in the observation group was higher (P<0.05), the operative time, intraoperative blood loss, visual analogue VAS score on the first day after surgery and length of hospital stay were lower (P<0.05), and the stone clearance rate was higher 1 week and 1 month after surgery (P<0.05). The levels of serum NLR, CRP, Scr and BUN on the 1st and 3rd day after surgery were lower (P<0.05), and the complications 3 months after surgery and the recurrence rate 1 year after surgery were lower (P<0.05).?? Conclusion: STL in the treatment of complex upper ureteral calculi can improve the clinical effect, increase the stone clearance rate, improve the level of inflammation and kidney function, and reduce the incidence of complications and stone recurrence. |
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