| 华英.参苓白术散合苍耳子散联合布地奈德鼻腔雾化序贯治疗儿童急性鼻窦炎脾虚湿困型的疗效观察[J].浙江中西医结合杂志,2025,35(4): |
| 参苓白术散合苍耳子散联合布地奈德鼻腔雾化序贯治疗儿童急性鼻窦炎脾虚湿困型的疗效观察 |
|
| 投稿时间：2024-09-22 修订日期：2025-02-11 |
| DOI： |
| 中文关键词: 儿童 急性鼻窦炎 参苓白术散 苍耳子散 布地奈德鼻腔雾化 脾虚湿困型 |
| 英文关键词:: Children acute sinusitis Shenqi Baizhu Powder Fructus Xanthii Powder Budesonide nasal atomization spleen deficiency and dampness stagnation type. |
| 基金项目: |
|
| 摘要点击次数: 283 |
| 全文下载次数: 1 |
| 中文摘要: |
| 【】 目的 观察参苓白术散合苍耳子散联合布地奈德鼻腔雾化序贯治疗儿童急性鼻窦炎脾虚湿困型的疗效。方法 将80例脾虚湿困型急性鼻窦炎患儿随机分为2组,对照组给予阿莫西林克拉维酸钾颗粒口服及布地奈德鼻喷雾剂喷鼻治疗,阿莫西林克拉维酸钾颗粒疗程2周,布地奈德鼻喷雾剂疗程4周,观察组给予阿莫西林克拉维酸钾干混悬剂加参苓白术散合苍耳子散加减治疗2周,2周后序贯给予布地奈德鼻腔雾化2周,2组患儿疗程均为4周。4周后比较2组治疗前、后视觉模拟评分法(VAS)评分、中医症状及体征积分、鼻窦CT检查Lund—Mackay评分、总临床疗效及不良反应发生的情况,并比较2组3个月内的复发率。结果 2组治疗后VAS评分均较本组治疗前降低(P<0.05),且观察组显著低于对照组(P<0.05)；2组治疗后鼻渊症状及体征积分均较治疗前下降(P<0.05),且观察组显著低于对照组(P<0.05)；2组治疗后鼻窦CT Lund—Mackey评分较治疗前下降(P<0.05),且观察组显著低于对照组(P<0.05)；两组治疗后临床总疗效比较,观察组总有效率为 92.1%,对照组为 57.9%,两组比较差异显著(P<0.05)；2组治疗后复发率比较,观察组复发率为18.4%,对照组为 47.4%,两组比较差异有显著性(P<0.05)；且不良反应少。 结论 参苓白术散合苍耳子散联合布地奈德鼻腔雾化序贯治疗儿童急性鼻窦炎脾虚湿困型急性鼻窦炎的疗效显著,安全性高。 |
| 英文摘要: |
| Objective To observe the efficacy of Shenqi Baizhu Powder combined with Fructus Xanthii Powder combined with Budesonide nasal nebulizer sequential treatment for children with acute sinusitis of spleen deficiency and dampness stagnation type. Methods 80 cases of children with acute sinusitis of spleen deficiency and dampness stagnation type were randomly divided into 2 groups, the control group was given Amoxicillin Clavulanate Potassium Granules orally and Budesonide Nasal Spray, Amoxicillin Clavulanate Potassium Granules for 2 weeks and Budesonide Nasal Spray for 4 weeks, the observation group was given Amoxicillin Clavulanate Potassium Dry Suspension plus Shenqi Baizhu Powder with Fructus Xanthii Powder plus or minus treatment for 2 weeks, and the sequential treatment of Budesonide was given for 2 weeks later. Budesonide nasal nebulization was given for 2 weeks, and the duration of treatment was 4 weeks in both groups. 4 weeks later, the visual analog scale (VAS) scores, Chinese medicine signs and symptoms scores, Lund-Mackay scores of sinus CT examination, total clinical efficacy and the occurrence of adverse reactions were compared before and after the treatment in the 2 groups, and the recurrence rates within 3 months were also compared between the 2 groups. Results The VAS scores of the 2 groups after treatment were lower than that before treatment in this group (P<0.05), and the observation group was significantly lower than that of the control group (P<0.05); the nasal abyss symptom and sign scores of the 2 groups after treatment were lower than that before treatment (P<0.05), and the observation group was significantly lower than that of the control group (P<0.05); the sinus CT Lund- Mackey score after treatment of the two groups decreased compared with the pre-treatment (P<0.05), and the observation group was significantly lower than the control group (P<0.05); the total clinical efficacy of the two groups after treatment, the observation group total effective rate was 92.1%, and the control group was 57.9%, the difference between the two groups is significant (P<0.05); the recurrence rate of the two groups after treatment, the observation group recurrence rate was 18.4%, and the control group 47.4%, the difference between the two groups is significant (P<0.05). Comparing the recurrence rates of the two groups after treatment, the recurrence rate of the observation group was 18.4%, and that of the control group was 47.4%, and the difference between the two groups was significant (P<0.05); and there were less adverse reactions. Conclusion Shenqi Baizhu Powder and Fructus Xanthii Powder combined with Budesonide nasal nebulization sequential treatment of acute sinusitis in children with spleen deficiency and dampness stagnation type acute sinusitis has significant efficacy and high safety. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
