| 吕梦奕,林卢学,周帆.基于网状Meta分析的哺乳期乳头皲裂预防措施评价[J].浙江中西医结合杂志,2025,35(6): |
| 基于网状Meta分析的哺乳期乳头皲裂预防措施评价 |
| Evaluation of Preventive Measures for Cracked Nipples during Lactation Based on Network Meta-Analysis |
| 投稿时间：2024-10-06 修订日期：2025-03-12 |
| DOI： |
| 中文关键词: 哺乳期乳头皲裂 预防 网状Meta分析 干预措施 有效性评价 |
| 英文关键词:cracked nipples during lactation prevention network meta-analysis interventions effectiveness evaluation |
| 基金项目:浙江省中医药科技计划项目(2024ZL997) |
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| 中文摘要: |
| 目的:评价不同干预措施对哺乳期乳头皲裂的预防效果。方法:计算机检索中国知网、万方、中国生物医学数据库、PubMed、The Cochrane Library、Web of Science和EMbase数据库,纳入近20年国内外公开发表文献,筛选出符合标准的随机对照试验,运用网状meta分析比较文献中不同干预措施预防哺乳期乳头皲裂的有效性。结果:共纳入研究20篇,涉及15种干预措施,其中常规护理、乳汁、羊脂膏之间直接比较的研究数最多,羊脂膏、蓝油径软膏、可可脂、蜂蜜、橄榄油、胎脂、薄荷、椰子油、茶树油的预防效果优于常规护理(P＜0.05)；唇膏、橄榄油、胎脂、茶树油的预防效果优于乳汁(P＜0.05)；橄榄油、茶树油的预防效果优于羊脂膏(P＜0.05)。概率排序结果提示预防效果最优为茶树油,最末为常规护理。结论:茶树油在预防乳头皲裂方面表现最佳,其次是橄榄油、胎脂等多种天然制剂。本研究通过网状Meta分析系统评估了多种预防哺乳期乳头皲裂的干预措施,为哺乳期女性提供了更多有效的预防选择。 |
| 英文摘要: |
| Objective To evaluate the effectiveness of different interventions in preventing nipple cracking during lactation. Methods A computerized search of CNKI, Wanfang, CBM, PubMed, The Cochrane Library, Web of Science, and EMbase databases was conducted to incorporate domestic and international published literature in the past 20 years, to screen out randomized controlled trials that met the criteria, and to compare the efficacy of different interventions to prevent nipple cracking during lactation in the literature by using network meta-analysis. Results A total of 20 studies involving 15 interventions were included, with the largest number of studies directly comparing between routine care, breast milk and lanolin. Lanolin, guaiazulene , cocoa butter, honey, olive oil, vernix caseosa, peppermint, coconut oil, and tea tree oil were more effective in preventing chapped nipples than routine care (P < 0.05); lip balm, olive oil, vernix caseosa, and tea tree oil were more effective in preventing chapped nipples than breast milk (P < 0.05); the preventive effect of olive oil and tea tree oil was superior to lanolin (P < 0.05). The results of probability ranking suggested that the best preventive effect was tea tree oil and the last was conventional care. conclusion Tea tree oil performed best in preventing nipple cracking, followed by various natural agents such as olive oil and vernix caseosa. This study evaluated multiple interventions for prevention of cracked nipples during lactation through a network meta-analysis system, which provides more effective prevention options for lactating women. |
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