| 朱方语.探讨强肾通督针灸联合补阳还五汤对肾虚血瘀型腰椎间盘突出症（LDH）患者的影响[J].浙江中西医结合杂志,2026,36(1): |
| 探讨强肾通督针灸联合补阳还五汤对肾虚血瘀型腰椎间盘突出症（LDH）患者的影响 |
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| 投稿时间：2024-10-22 修订日期：2025-03-24 |
| DOI： |
| 中文关键词: 腰椎间盘突出症 强肾通督针灸 补阳还五汤 浊毒理论 炎症因子 自由基 |
| 英文关键词:Lumbar disc herniation Qiangshen Tongdu acupuncture Buyang Huanwu decoction Turbid toxin theory Inflammatory factors Free radicals |
| 基金项目:项目名称：浙江省中医药科技计划项目 项目编号：2024ZF173 |
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| 中文摘要: |
| 目的? 探讨强肾通督针灸联合补阳还五汤对肾虚血瘀型腰椎间盘突出症(LDH)患者的影响。方法? 将2021年1月至2023年9月期间本院收治的162例肾虚血瘀型LDH患者,随机分为对照组(补阳还五汤治疗)与研究组(强肾通督针灸联合补阳还五汤治疗),81例/组。比较两组疗效、腰腿部疼痛(VAS)评分、腰椎功能(JOA)评分与中医症候积分、炎症因子及自由基代谢指标。结果? 研究组治疗后的临床疗效高于对照组(P＜0.05)。与治疗前相比,两组治疗后的VAS评分均降低,且JOA评分升高,且研究组VAS评分、JOA评分改善均优于对照组(P＜0.05)。与治疗前相比,两组治疗后的中医症候主证、次症积分均降低,且研究组低于对照组(P＜0.05)。与治疗前相比,两组治疗后的血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平均降低,且研究组低于对照组(P＜0.05)。与治疗前相比,两组治疗后的血清超氧化物歧化酶(SOD)活性均较治疗前升高,血清丙二醛(MDA)、一氧化氮(NO)水平均降低,研究组低于对照组(P＜0.05)。结论? 强肾通督针灸联合补阳还五汤治疗肾虚血瘀型LDH疗效显著,可在一定程度上减轻患者疼痛症状,改善其腰椎功能,降低炎症因子水平,改善自由基代谢。 |
| 英文摘要: |
| Objective Exploring the effect of acupuncture for strengthening the kidneys and promoting the governor combined with tonifying the yang and restoring the five tangs on patients with lumbar disc herniation (LDH) of the kidney deficiency and blood stasis type. Methods 162 patients with kidney deficiency and blood stasis type LDH admitted to our hospital between January 2021 and September 2023were randomly divided into the control group (treatment with tonifying yang and returning five soups) and the study group (treatment with strong kidney and tongdu acupuncture combined with tonifying yang and returning five soups), 81 cases/group. The two groups were compared in terms of therapeutic efficacy, low back and leg pain (VAS) scores, lumbar spine function (JOA) scores and TCM symptom scores, inflammatory factors and free radical metabolism indexes. Results The clinical efficacy of the study group after treatment was higher than that of the control group (P<0.05). Compared with before treatment, both groups showed a decrease in VAS scores and an increase in JOA scores after treatment, and the improvement in VAS and JOA scores in the study group was better than that in the control group (P<0.05). Compared with before treatment, the scores of the main and secondary symptoms of traditional Chinese medicine in both groups decreased after treatment, and the study group was lower than the control group (P<0.05). Compared with before treatment, the levels of serum tumor necrosis factor - α (TNF - α), interleukin-6 (IL-6), and C-reactive protein (CRP) in both groups decreased after treatment, and the study group was lower than the control group (P<0.05). Compared with before treatment, the activity of serum superoxide dismutase (SOD) increased in both groups after treatment, while the levels of serum malondialdehyde (MDA) and nitric oxide (NO) decreased. The study group was lower than the control group (P<0.05).Conclusion The efficacy of acupuncture and moxibustion combined with tonifying yang and restoring five soups in treating kidney deficiency and blood stasis type LDH is remarkable, which can reduce the pain symptoms of the patients to a certain extent, improve their lumbar spine function, reduce the level of inflammatory factors, and improve the metabolism of free radicals. |
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