| 赵柯超,金雨虹.血清前白蛋白水平对心脏外科术后患者长期预后的影响研究[J].浙江中西医结合杂志,2026,36(4): |
| 血清前白蛋白水平对心脏外科术后患者长期预后的影响研究 |
| The Impact of Serum Prealbumin Levels on the Long-Term Prognosis of Patients After Cardiac Surgery |
| 投稿时间：2024-11-15 修订日期：2025-12-12 |
| DOI： |
| 中文关键词: 心脏外科手术 血清前白蛋白 预后 影响因素分析 |
| 英文关键词:Cardiac surgery serum prealbumin prognosis factor analysis |
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| 中文摘要: |
| 目的 探讨术前血清前白蛋白水平对接受心脏手术患者术后生存率的预测价值。方法 纳入2021年1月1日至2021年12月31日在宁波大学附属李惠利医院接受心脏外科手术治疗的患者372例,在手术前24小时内抽取血清前白蛋白,再进行随访,随访截止日期为2023年12月31日。依据术前血清前白蛋白水平将其分为≥200 mg/L组和＜200 mg/L组。比较两组患者一般资料及全因死亡发生率,比较两组患者全因死亡的生存曲线,并采用多因素Cox回归分析全因死亡的影响因素。结果 血清前白蛋白水平＜200 mg/L的患者组全因死亡率显著高于≥200 mg/L组(P < 0.001)。两组患者全因死亡的生存曲线比较,差异有统计学意义(P < 0.05)。多因素Cox回归分析表明,血清前白蛋白＜200 mg/L是心脏外科术后死亡的独立预测因子(OR=5.274,95% CI: 2.226-12.498,P < 0.001)。结论 血清前白蛋白水平与心脏外科术后生存率密切相关,术前低前白蛋白水平可能是术后不良预后的重要预测因子。 |
| 英文摘要: |
| Objective To investigate the predictive value of preoperative serum prealbumin levels on postoperative survival rates in patients undergoing cardiac surgery. Methods A total of 372 patients who underwent cardiac surgery at Li Huili Hospital affiliated with Ningbo University from January 1, 2021, to December 31, 2021, were included in the study. Serum prealbumin was collected within 24 hours before surgery, followed by a follow-up period ending on December 31, 2023. Patients were divided into two groups based on preoperative serum prealbumin levels: ≥200 mg/L and <200 mg/L. General data and all-cause mortality rates were compared between the two groups, and survival curves for all-cause mortality were analyzed. Multivariate Cox regression analysis was performed to assess the influencing factors for all-cause mortality. Results The all-cause mortality rate of the group with serum prealbumin levels <200 mg/L was significantly higher than that of the ≥200 mg/L group (P < 0.001). The comparison of survival curves |
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