浙江中西医结合杂志

胡文雯,何颖雪,郑谊谊,潘璐璐,潘彬惠,程雅倩,邵玲就,邵国建.维持性血液透析患者合并抑郁症状的相关因素分析[J].浙江中西医结合杂志,2026,36(7):

维持性血液透析患者合并抑郁症状的相关因素分析

Analysis of factors related to depression symptoms in patients on maintenance hemodialysis

投稿时间：2024-12-13 修订日期：2026-06-23

DOI：

英文关键词:hemodialysis depression related factors

基金项目:温州市科学技术协会（NO.kjfw16）

作者	单位	E-mail
胡文雯	温州市中心医院	wzzxhww@163.com
何颖雪	温州市中心医院
郑谊谊	温州市中心医院
潘璐璐	温州市中心医院
潘彬惠	温州市中心医院
程雅倩	温州市中心医院
邵玲就	温州市中心医院
邵国建^*	温州市中心医院	wzshaogj@163.com

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中文摘要:

【目的】评估维持性血液透析（MHD）患者合并抑郁症状的患病率及探讨其相关因素。【方法】纳入2023年9-10月在温州市中心医院医疗集团下属的三家透析中心接受维持性血液透析的567例患者。采用PHQ-9抑郁症状筛查量表评估抑郁症状的发生率，并根据其评估结果分为抑郁组和无抑郁组，收集他们的一般资料及实验室指标进行统计学分析，找出MHD患者合并抑郁的独立危险因素。【结果】 MHD患者合并抑郁症状的发生率为51%，有抑郁症状的患者中女性比例、未婚者比例、透析龄、增重量、收缩压、CRP均高于无抑郁症状组，白蛋白水平低于无抑郁症状组，差异有统计学意义（P＜0.05）。二元Logistic回归分析得出性别、婚姻状态、增重、透析龄、白蛋白水平是维持性血透患者合并抑郁症状的独立危险因素。【结论】维持性血液透析患者抑郁症状的发生率较高，其中女性、未婚、增重多、透析龄增长是患者合并抑郁症状的独立危险因素，白蛋白水平升高是保护性因素。

英文摘要:

[Objective] To evaluate the prevalence of depression symptoms in patients undergoing maintenance hemodialysis (MHD) and to explore its related factors. [Methods] A total of 567 MHD patients at three dialysis centers affiliated with Wenzhou Central Hospital Medical Group were enrolled from September to October 2023. The PHQ-9 Depression Symptom Screening Scale was used to assess the incidence of depression symptoms. The patients were divided into a depressiom group and a non-depression group based on the assessment result. General information and laboratory indicators were collected for statistical analysis to identify the independent risk factors for depression in MHD patients. [Results] The incidence of depressive symptoms among MHD patients was 51%. Among patients with depressive symptoms, the proportion of females, unmarried individuals,dialysis age, weight gain, systolic blood pressure and CRP levels were higher than those in the non-depressive symptoms group, while albumin levels were lower. The differences were statistically significant (P < 0.05).Binary logistic regression analysis showed that gender, marital status, weight gain, dialysis age, and albumin level were independent risk factors for depression in MHD patients . [Conclusion] The incidence of depressive symptoms is high in maintenance hemodialysis patients.?Female gender, being unmarried, greater weight gain, and increased dialysis age are independent risk factors for depression, while elevated albumin levels are a protective factor.

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