| 王蓉.富含血小板血浆在糖尿病足溃疡恢复期临床应用价值研究[J].浙江中西医结合杂志,2026,36(7): |
| 富含血小板血浆在糖尿病足溃疡恢复期临床应用价值研究 |
| Clinical application value of platelet-rich plasma in convalescent stage of diabetic foot ulcer |
| 投稿时间：2025-01-18 修订日期：2026-06-09 |
| DOI： |
| 中文关键词: 富含血小板血浆 糖尿病足溃疡 恢复期 应用 |
| 英文关键词:platelet-rich plasma Diabetic foot ulcer Convalescence period Apply |
| 基金项目:湖州市科学技术局项目 编号：2023GY101 |
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| 中文摘要: |
| 【】目的:探讨分析富含血小板血浆(PRP)在糖尿病足溃疡恢复期的临床应用价值。方法:选取2022年1月~2024年12月,医院收治的60例2型糖尿病足溃疡患者作为研究对象,按照随机数字表法将其分对照组和观察组,各30例。对照组采用综合治疗,观察组在对照组治疗基础上应用PRP技术治疗。比较两组创面面积大小、创面愈合时间、疼痛程度评分、肉芽组织覆盖率以及治疗期间不良反应情况。结果:治疗后,观察组创面面积低于对照组(P<0.05)。观察组创面愈合时间低于对照组；而治疗1周、2周后,观察组肉芽组织覆盖率均大于对照组(P<0.05)。治疗后,观察组疼痛评分低于对照组(P<0.05)。观察组不良反应发生率低于对照组(P<0.05)。结论:富含血小板血浆在糖尿病足溃疡恢复期中的应用效果确切,能够减少创面面积,缩短创面愈合时间,减轻患者疼痛程度,提高肉芽组织覆盖率,且安全性较高,值得临床推广应用。 |
| 英文摘要: |
| 【】Objective: To explore the therapeutic efficacy of platelet-rich plasma (PRP) in the recovery phase of diabetic foot ulcers. Methods: Between January 2022 and December 2024, 60 patients with type 2 diabetes and foot ulcers were enrolled and randomly divided into a control group and an experimental group, each comprising 30 individuals. The control group received standard comprehensive care, while the experimental group was treated with PRP in addition to the standard care. The study compared wound size, healing duration, pain levels, granulation tissue coverage, and adverse events between the two groups. Results: Post-treatment, the experimental group exhibited a smaller wound area compared to the control group (P<0.05). The time required for wound closure was also shorter in the experimental group. At 1 and 2 weeks post-treatment, the experimental group showed greater granulation tissue coverage (P<0.05). Pain scores in the experimental group were lower than those in the control group (P<0.05). Additionally, the rate of adverse events was lower in the experimental group (P<0.05). Conclusion: The use of platelet-rich plasma in the rehabilitation of diabetic foot ulcers is highly effective, as it reduces wound size, accelerates healing, decreases pain, enhances granulation tissue formation, and is associated with minimal side effects, making it a valuable clinical intervention. |
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