欢迎访问浙江中西医结合杂志   今天是   加入收藏   |   设为首页
屠婉青,谢小红.基于肠道菌群研究机制探讨李东垣学术思想在乳腺癌治疗中的应用[J].浙江中西医结合杂志,2026,36(4):
基于肠道菌群研究机制探讨李东垣学术思想在乳腺癌治疗中的应用
Exploring Li Dong-yuan's Spleen-Stomach Theory in Breast Cancer Treatment: A Gut Microbiota Perspective
投稿时间:2025-02-22  修订日期:2026-03-12
DOI:
中文关键词:  肠道菌群  李东垣  脾胃学派  乳腺癌  中医治疗
英文关键词:Gut Microbiota  Li Dong-yuan  Spleen-Stomach Theory  Breast Cancer  Traditional Chinese Medicine Treatment
基金项目:
作者单位E-mail
屠婉青 浙江中医药大学 1245409313@qq.com 
谢小红* 浙江省中医院 xxh666857@163.com 
摘要点击次数: 5
全文下载次数: 0
中文摘要:
      现代研究已证明肠道菌群通过代谢产物参与人体多项生理、病理过程,并与乳腺癌的发病、复发、转移、治疗效果密切相关。李东垣是脾胃学派的创始者,他的学术思想以“内伤脾胃,百病由生”为中心,创造性提出了“阴火”的病理概念以及甘温除热的治法。肠道菌群属于中医脾胃的范畴,肠道菌群各种理论观点均与李东垣的学术思想相合。故本文拟基于肠道菌群的各项研究探讨运用李东垣学术思想论治乳腺癌,阐述其现代科学内涵,并为中医药在乳腺癌临床治疗方面提供了新的理论框架与实施方法。
英文摘要:
      Contemporary research has demonstrated that gut microbiota participates in various human physiological and pathological processes through metabolites, exhibiting significant correlations with the pathogenesis, recurrence, metastasis, and therapeutic efficacy of breast cancer. Li Dong-yuan, founder of the Spleen-Stomach Theory in traditional Chinese medicine (TCM), established the core doctrine that "impairment of the spleen-stomach system underlies all pathologies," innovatively proposing the pathological concept of "yin fire" and a therapeutic strategy utilizing herbal tonics with sweet and warm properties to eliminate heat. Notably, gut microbiota – falling under the TCM theoretical framework of spleen-stomach system homeostasis – demonstrates remarkable consistency with Li Dong-yuan's academic postulations. This study integrates contemporary gut microbiota research with Li Dongyuan's theoretical system to explore its applicability in breast cancer treatment, aiming to elucidate the modern scientific rationale behind this TCM approach while proposing a novel theoretical framework and practical methodologies for integrating TCM principles into clinical breast cancer management.
查看全文  查看/发表评论  下载PDF阅读器
关闭