| Objective Because the pain after cesarean section seriously affects the maternal recovery, the analgesic effect of hydromorphone epidural cavity combined with intravenous injection was carried out to optimize the analgesic plan, reduce the maternal pain and promote the postoperative recovery. Methods From November 20204 to February 2025 were selected for prospective study, which were divided into reference group and study group by digital table method, with 40 cases in each group. The postoperative hydromorphone intravenous analgesia pump formula was: 0.1mg / kg hydromorphone injection + 0.25mg palonosetron injection, with normal saline added to 100ml. The reference group injected 5ml of normal saline in the retroperitoneal epidural cavity, and the study group injected a combined intravenous injection of 0.3mg of hydromorphone diluted to 5ml in the epidural cavity after the peritoneal suture. The incidence of adverse reactions such as postoperative pain scores, postoperative Ramsay sedation score, nausea, vomiting and itching were compared between the two groups.Results The NRS scores at 4h, 12h and 24h after surgery in the study group were lower than that of the reference group, and the difference was statistically significant (P <0.05), while the 48h pain scores (P> 0.05); the Ramsay sedation scores at 4 h, 12h, 24h, 24 h and 48h and the scores were 2-4 points (P <0.05); comparing the nausea, vomiting and pruritus (P> 0.05). Conclusion Hydromorphone epidural combined for postoperative analgesia can effectively reduce maternal pain, improve sedative satisfaction, and reduce the incidence of adverse reactions, and provide an optimized scheme for postoperative analgesia. |
