| 蔡芳婷,何媚燕,黄晖,张尊敬.慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭患者的营养状况及影响因素分析[J].浙江中西医结合杂志,2026,36(2): |
| 慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭患者的营养状况及影响因素分析 |
| Analysis of the current nutritional status and influencing factors of patients with acute exacerbation of chronic obstructive pulmonary disease combined with type II respiratory failur |
| 投稿时间：2025-03-20 修订日期：2025-06-24 |
| DOI： |
| 中文关键词: 慢性阻塞性肺疾病急性加重期 Ⅱ型呼吸衰竭 营养 NRS2002 影响因素 |
| 英文关键词:Acute exacerbation of chronic obstructive pulmonary disease Type II respiratory failure Nutrition NRS2002 Influencing factors |
| 基金项目:浙江省中医药科技计划项目(No.2025ZR227)；国家中医优势专科丽水市中医院肺病科 |
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| 中文摘要: |
| 目的：了解慢性阻塞性肺疾病急性加重期（AECOPD）合并Ⅱ型呼吸衰竭患者的营养状况，并分析其影响因素。方法：回顾性分析2020年1月至2024年11月于浙江省丽水市中医院呼吸科住院的AECOPD合并Ⅱ型呼吸衰竭患者205例，根据入院时NRS-2002营养风险筛查量表分为营养良好组和营养不良风险组，单因素和多因素回归分析AECOPD合并Ⅱ型呼吸衰竭患者营养风险的影响因素。结果：205例AECOPD合并Ⅱ型呼吸衰竭患者中，营养良好组129例（62.93%），营养不良风险组76例（37.07%）。多因素Logistic回归分析显示，婚姻状况(OR=0.258，95%CI：0.076～0.871)、BMI(OR=0.691，95%CI：0.547～0.873)、CAT问卷评分(OR=1.353，95%CI：1.177～1.557)、COPD一年内急性加重次数(OR=1.663，95%CI：1.168～2.367)是患者营养风险的主要影响因素（P＜0.05）。结论：AECOPD合并Ⅱ型呼吸衰竭患者的营养风险发生率较高，医护人员应对低BMI、病情症状严重、疾病反复发作的患者给予更高的关注，提供针对性的个体化营养支持与帮助，以促进此类患者临床结局的良好转归。 |
| 英文摘要: |
| Objective: To understand the nutritional status of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with type II respiratory failure and to analyze the factors affecting it. Methods: A retrospective analysis was conducted on 205 patients with AECOPD combined with type II respiratory failure who were hospitalized in the respiratory department of Lishui Traditional Chinese Medicine Hospital, Zhejiang Province, between January 2020 and November 2024. Patients were categorized into a well-nourished group and a malnutrition risk group based on the NRS-2002 Nutritional Risk Screening Scale at the time of admission. Factors influencing nutritional risk in patients with AECOPD combined with type II respiratory failure were analyzed by univariate and multivariate Logistic regression. Results: Among the 205 patients, 129 (62.93%) were in the well nourished group and 76 (37.07%) were in the malnutrition risk group. Multivariate Logistic regression analysis showed that marital status (OR = 0.258, 95% CI: 0.076 to 0.871), BMI (OR = 0.691, 95% CI: 0.547 to 0.873), CAT questionnaire score (OR = 1.353, 95% CI: 1.177 to 1.557), and number of acute exacerbations in one year of COPD (OR = 1.663, 95% CI : 1.168 to 2.367) were the main factors influencing the nutritional risk of patients (P < 0.05). Conclusion: Patients with AECOPD combined with type II respiratory failure have a high incidence of nutritional risk, and healthcare professionals should pay higher attention to patients with low BMI, severe disease symptoms, and recurrent disease exacerbations. It’s essential to provide targeted and individualized nutritional support and assistance to promote good prognostic outcomes in such patients. |
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