| 朱龙.强迫症合并抑郁患者童年创伤与自我控制、内隐外显记忆损伤的关系[J].浙江中西医结合杂志,2026,36(4): |
| 强迫症合并抑郁患者童年创伤与自我控制、内隐外显记忆损伤的关系 |
| The relationship between childhood trauma and self-control, implicit and explicit memory impairment in patients with obsessive-compulsive disorder complicated with depression |
| 投稿时间：2025-06-24 修订日期：2025-12-28 |
| DOI： |
| 中文关键词: 强迫症 抑郁症 童年创伤 自我控制 内隐记忆 外显记忆 |
| 英文关键词:Obsessive-compulsive disorder depressive disorder childhood trauma self-control implicit memory explicit memory |
| 基金项目:建德市发展科技计划 计划编码：2020YW16 |
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| 中文摘要: |
| 【】目的:评估强迫症合并抑郁患者童年创伤水平与自我控制、内隐外显记忆的相关性。方法:取选我院2023年1月-2024年12月间收治的强迫症合并抑郁患者68例,按照童年创伤水平差异将患者分为高创伤组35例(CTQ评分≥52.50)和低创伤组33例(CTQ评分＜52.50),比较两组患者自我控制、内隐外显记忆水平。评估患者儿童创伤问卷(CTQ)评分与自我控制量表(SCS)评分、内隐记忆重复启动任务范式指标、韦氏记忆量表(WMS)评分的相关性。结果:强迫症合并抑郁患者童年创伤水平与冲动控制(r=-0.868)、情绪调节(-0.643)功能呈负相关；与内隐记忆重复启动任务中重复刺激准确率(r=-0.709)、新刺激准确率(r=-0.643)呈负相关；与重复刺激反应时间(0.838)和新刺激反应时间(0.870)呈正相关；与外显记忆中的即时记忆(r=-0.773)、延迟记忆(r=-0.789)、工作记忆(r=-0.793)、视觉记忆(r=-0.695)和听觉记忆(r=-0.750)呈负相关,差异有统计学意义(P＜0.05)。结论:强迫症合并抑郁患者童年创伤水平与自我控制能力、内隐外显记忆损伤密切相关,可通过探讨童年创伤、自我控制和记忆功能之间的关系,为识别高风险群体,制定个性化治疗提供依据。 |
| 英文摘要: |
| Objective :To evaluate the correlation between childhood trauma level and self-control, implicit and explicit memory in patients with obsessive-compulsive disorder and depression.Methods : 68 patients with obsessive-compulsive disorder and depression admitted to our hospital from January 2023 to December 2024 were selected. According to the difference of childhood trauma level, the patients were divided into high trauma group ( 35 cases, CTQ score ≥ 52.50 ) and low trauma group ( 33 cases, CTQ score < 52.50 ). The levels of self-control, implicit and explicit memory were compared between the two groups. The correlation between children 's trauma questionnaire ( CTQ ) score and self-control scale ( SCS ) score, implicit memory repetition priming task paradigm index and Wechsler memory scale ( WMS ) score was evaluated.Results:The level of childhood trauma in patients with obsessive-compulsive disorder and depression was negatively correlated with impulse control ( r = -0.868 ) and emotion regulation ( -0.643 ). There was a negative correlation between the accuracy of repeated stimulation ( r = -0.709 ) and the accuracy of new stimulation ( r = -0.643 ) in the repeated priming task of implicit memory. It was positively correlated with repeated stimulation reaction time ( 0.838 ) and new stimulation reaction time ( 0.870 ). There was a negative correlation between and immediate memory ( r = -0.773 ), delayed memory ( r = -0.789 ), working memory ( r = -0.793 ), visual memory ( r = -0.695 ) and auditory memory ( r = -0.750 ) in explicit memory, and the difference was statistically significant ( P < 0.05 ).Conclusion:The level of childhood trauma in patients with obsessive-compulsive disorder complicated with depression is closely related to self-control ability and implicit explicit memory impairment. By exploring the relationship between childhood trauma, self-control and memory function, it can provide a basis for identifying high-risk groups and formulating personalized treatment. |
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