| 袁红卫,梅敏莎,张同旭.利培酮联合中医五禽戏对康复期精神分裂症患者精神症状及焦虑抑郁的影响[J].浙江中西医结合杂志,2026,36(7): |
| 利培酮联合中医五禽戏对康复期精神分裂症患者精神症状及焦虑抑郁的影响 |
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| 投稿时间：2025-09-29 修订日期：2026-06-15 |
| DOI： |
| 中文关键词: 利培酮 中医五禽戏 康复期精神分裂症患者 精神症状 焦虑抑郁 |
| 英文关键词:Risperidone Traditional Chinese Medicine Five-Animal Exercises patients with schizophrenia in the rehabilitation period mental symptoms anxiety and depression |
| 基金项目:丽水市科技计划项目（2022SJZCO45） |
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| 中文摘要: |
| 目的:探讨利培酮联合中医五禽戏对康复期精神分裂症患者精神症状及焦虑抑郁的影响。方法:选取2022年9月至2024年12月时间段,我院收治精神分裂症患者136例,且处于康复期,依据随机数字表法分为2组,均为68例。对照组给予常规抗精神药物氯丙嗪、奋乃静药物和康复干预,研究组在对照组基础上,进行利培酮联合中医五禽戏干预。比较两组干预前后阳性与阴性症状量表(PANSS)评分、抑郁量表(HAMD)评分、焦虑量表(HAMA)评分及患者生活质量(SQLS)评分水平的变化。结果:干预后,研究组临床疗效(92.64%)大幅度高于对照组临床疗效(73.53%)(P<0.05)；研究组PANSS评分中阳性症状分(15.75±1.58 vs? 12.50±1.36)、阴性症状分(16.37±1.61 vs 13.15±1.43)及一般精神病理分(31.50±6.62 vs 23.46±5.42)均有所降低,且低于对照组(P<0.05)；研究组HAMD评分(13.88±4.07 vs 9.60±0.88)、HAMA(10.84±4.64 vs 8.46±3.66)评分均降低,且低于对照组(P<0.05)；研究组SQLS评分的动力/精力(32.50±3.21 vs 27.24±2.09)、心理社会(23.81±3.86 vs 18.06±2.81)及症状/副作用分(17.53±2.26 vs 14.12±1.83)均降低,且低于对照组(P<0.05)。结论:利培酮联合中医五禽戏能有效改善康复期精神分裂症患者的精神症状,减轻焦虑抑郁情绪,提高患者的生活质量。 |
| 英文摘要: |
| Objective:To explore the effects of risperidone combined with traditional Chinese medicine Wuqinxi on the mental symptoms, anxiety and depression of patients with schizophrenia in the rehabilitation period. Methods: From September 2022 to December 2024, 136 patients with schizophrenia who were in the recovery period and admitted to our hospital were selected and randomly divided into two groups of 68 cases each according to the random number table method. The control group was given conventional antipsychotic drugs such as chlorpromazine and perphenazine and rehabilitation intervention. The study group was given risperidone combined with traditional Chinese medicine Wuqinxi intervention on the basis of the control group. The changes in Positive and Negative Syndrome Scale (PANSS) scores, Hamilton Depression Scale (HAMD) scores, Hamilton Anxiety Scale (HAMA) scores and Quality of Life Scale for Schizophrenia (SQLS) scores before and after intervention were compared between the two groups. Results: After intervention, the clinical efficacy of the study group (92.64%) was significantly higher than that of the control group (73.53%) (P < 0.05); the positive symptom score (15.75±1.58 vs 12.50±1.36), negative symptom score (16.37±1.61 vs 13.15±1.43) and general psychopathology score (31.50±6.62 vs 23.46±5.42) of the PANSS score in the study group were all decreased, and were lower than those of the control group (P < 0.05); the HAMD score (13.88±4.07 vs 9.60±0.88) and HAMA score (10.84±4.64 vs 8.46±3.66) of the study group were decreased, and were lower than those of the control group (P < 0.05); the scores of energy/energy (32.50±3.21 vs 27.24±2.09), psychological social (23.81±3.86 vs 18.06±2.81) and symptoms/side effects (17.53±2.26 vs 14.12±1.83) of the SQLS score in the study group were all decreased, and were lower than those of the control group (P < 0.05). Conclusion: Risperidone combined with traditional Chinese medicine Wuqinxi can effectively improve the mental symptoms of patients with schizophrenia in the rehabilitation period, reduce anxiety and depression, and improve the quality of life of patients. |
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